Silva Catarina, Palma Rita, Luz Rita, Almeida Manuela, Santos Antónia
Department of Obstetrics and Gynecology, Hospital Garcia de Orta, Almada, PRT.
Cureus. 2025 Jan 1;17(1):e76752. doi: 10.7759/cureus.76752. eCollection 2025 Jan.
Termination of pregnancy (TOP) in the second trimester accounts for less than 10% of all abortion procedures. Although it can be obtained by a surgical procedure, medical TOP is an effective and safe option. Prostaglandins have been used for cervical ripening in the second trimester but in the presence of uterine scars, the risk of uterine rupture rises. Given the increasing rate of cesarean deliveries worldwide, it is important to be aware of the risks associated with TOP in women with previous uterine scars. We describe a rare case, in a patient with a prior cesarean delivery, of a uterine rupture in a TOP at 20 weeks with a regimen of mifepristone-misoprostol and sulprostone.
妊娠中期终止妊娠（TOP）占所有堕胎手术的比例不到10%。尽管可以通过手术进行，但药物性TOP是一种有效且安全的选择。前列腺素已用于妊娠中期的宫颈成熟，但存在子宫瘢痕时，子宫破裂的风险会增加。鉴于全球剖宫产率不断上升，了解有既往子宫瘢痕的女性进行TOP相关的风险很重要。我们描述了一例罕见病例，一名既往有剖宫产史的患者，在妊娠20周使用米非司酮-米索前列醇和硫前列酮方案进行TOP时发生子宫破裂。
