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肺栓塞:儿童慢性胰腺炎急性发作的一种罕见表现。

Pulmonary Embolism: A Rare Presentation of Acute-on-Chronic Pancreatitis in Children.

作者信息

Iqbal Nazia, Mazhar Maryam, Noureen Sobia, Shujaat Eman, Malik Tahir, Seerat Iqtadar

机构信息

Department of Paediatrics Gastroenterology & Hepatology, Pakistan Kidney and Liver Institute, Lahore, PAK.

Department of Paediatric Gastroenterology & Hepatology, Pakistan Kidney and Liver Institute, Lahore, PAK.

出版信息

Cureus. 2025 Jan 1;17(1):e76768. doi: 10.7759/cureus.76768. eCollection 2025 Jan.

Abstract

Although splanchnic vein thrombosis may manifest as pancreatitis, it is rare to find venous thrombosis at other body sites. We present a rare case of acute-on-chronic pancreatitis in a patient who subsequently developed a deep venous thrombosis (DVT) of the right lower limb and pulmonary embolism (PE). A 14-year-old male presented with an acute history of upper abdominal pain, vomiting, and abdominal distension. Workup for pancreatitis was normal except for low hemoglobin and high serum pancreatic enzymes. The CT abdomen favored a diagnosis of acute-on-chronic pancreatitis with dilated pancreatic duct, multiple pseudo-pancreatic cysts, and saddle pulmonary embolus. He was treated with medical conservative therapy. For DVT and saddle PE, he was started on enoxaparin, which was later switched to rivaroxaban. A CT angiogram after three months of therapy with rivaroxaban showed the complete disappearance of the clot. Early detection of such life-threatening complications is important to achieve favorable outcomes in these patients.

摘要

尽管内脏静脉血栓形成可能表现为胰腺炎,但在身体其他部位发现静脉血栓形成的情况很少见。我们报告了一例罕见的慢性胰腺炎急性发作患者,该患者随后发生了右下肢深静脉血栓形成(DVT)和肺栓塞(PE)。一名14岁男性因上腹部疼痛、呕吐和腹胀的急性病史就诊。除血红蛋白低和血清胰酶高外,胰腺炎的检查结果正常。腹部CT倾向于诊断为慢性胰腺炎急性发作,伴有胰管扩张、多个假性胰腺囊肿和鞍状肺栓塞。他接受了内科保守治疗。对于DVT和鞍状PE,开始给他使用依诺肝素,后来换成利伐沙班。使用利伐沙班治疗三个月后的CT血管造影显示血栓完全消失。早期发现此类危及生命的并发症对于这些患者取得良好预后很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f57/11786000/2333133c11a1/cureus-0017-00000076768-i01.jpg

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