Calderone Andrea, Mazzurco Masi Vincenza Maura, De Luca Rosaria, Gangemi Antonio, Bonanno Mirjam, Floridia Daniela, Corallo Francesco, Morone Giovanni, Quartarone Angelo, Maggio Maria Grazia, Calabrò Rocco Salvatore
Department of Clinical and Experimental Medicine, University of Messina, Piazza Pugliatti, 1, 98122, Messina, Italy.
Università Degli Studi di Palermo, Piazza Marina, 61, 90133, Palermo, Italy.
Heliyon. 2025 Jan 11;11(2):e41917. doi: 10.1016/j.heliyon.2025.e41917. eCollection 2025 Jan 30.
Chronic pain (CP), affecting approximately 20 % of adults globally, imposes a profound burden on individuals and healthcare systems. This condition, characterized by persistent pain, muscle stiffness, and emotional distress, often results in a complex interplay of physical and psychological factors that exacerbate symptoms and hinder recovery. Biofeedback (BFB), a non-invasive intervention, offers a promising rehabilitation strategy by enabling individuals to monitor and self-regulate physiological responses, such as muscle tension, heart rate, and skin temperature. Through this process, BFB disrupts the vicious cycle of pain and stress, fostering relaxation, reducing muscle strain, and alleviating emotional distress. This systematic review aimed to examine the mechanisms underlying BFB's therapeutic effects in CP rehabilitation, specifically its ability to enhance self-regulation and promote relaxation to improve pain control. Furthermore, it aimed to evaluate the impact of BFB on key outcomes, including pain severity, functional capabilities, and quality of life, with the goal of guiding its integration into contemporary rehabilitation practices.
Following PRISMA guidelines, a systematic search was conducted in PubMed, Web of Science, and Embase (2014-2024) to identify studies on BFB for CP. Inclusion criteria included original research involving BFB as a primary or secondary intervention for CP, with outcomes related to pain management and rehabilitation. This review is registered on Open OSF (X5HPB).
BFB has shown consistent efficacy as a complementary therapy in CP management, offering significant reductions in pain intensity and enhancements in quality of life across diverse CP conditions. Mechanistically, BFB facilitates improved self-regulation by training patients to modulate physiological responses, such as muscle tension and heart rate variability, leading to better pain control and stress reduction.
BFB shows significant promise as a supplementary treatment for different CP disorders. The evidence that was examined shows that it is effective in improving how pain is perceived, increasing functional results, and boosting overall quality of life among a variety of patient groups.
慢性疼痛(CP)影响着全球约20%的成年人,给个人和医疗保健系统带来了沉重负担。这种疾病的特征是持续疼痛、肌肉僵硬和情绪困扰,常常导致身体和心理因素的复杂相互作用,从而加剧症状并阻碍康复。生物反馈(BFB)是一种非侵入性干预措施,通过使个体能够监测和自我调节生理反应,如肌肉紧张度、心率和皮肤温度,提供了一种有前景的康复策略。通过这个过程,BFB打破了疼痛和压力的恶性循环,促进放松,减轻肌肉紧张,并缓解情绪困扰。本系统评价旨在研究BFB在CP康复中治疗效果的潜在机制,特别是其增强自我调节和促进放松以改善疼痛控制的能力。此外,其旨在评估BFB对关键结局的影响,包括疼痛严重程度、功能能力和生活质量,目标是指导将其纳入当代康复实践。
按照PRISMA指南,在PubMed、科学网和Embase(2014 - 2024年)中进行系统检索,以识别关于BFB治疗CP的研究。纳入标准包括将BFB作为CP的主要或次要干预措施的原创研究,以及与疼痛管理和康复相关的结局。本评价已在开放的OSF(X5HPB)上注册。
BFB作为CP管理中的辅助疗法已显示出一致的疗效,在各种CP情况下,均能显著降低疼痛强度并提高生活质量。从机制上讲,BFB通过训练患者调节生理反应,如肌肉紧张度和心率变异性,促进更好的自我调节,从而实现更好的疼痛控制和压力减轻。
BFB作为不同CP疾病的辅助治疗显示出巨大潜力。所审查的证据表明,它在改善疼痛感知、提高功能结果以及提升各类患者群体的整体生活质量方面是有效的。