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结肠癌右半结肠切除术后胃轻瘫综合征的因素分析

Factor analysis of postsurgical gastroparesis syndrome after right hemicolectomy for colon cancer.

作者信息

Wang Gang, Pan Shengjie

机构信息

Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, P.R. China.

Department of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, P.R. China.

出版信息

Oncol Lett. 2025 Jan 23;29(3):154. doi: 10.3892/ol.2025.14900. eCollection 2025 Mar.

Abstract

The present study aimed to investigate factors influencing postsurgical gastroparesis syndrome (PGS) in patients with right-sided colon cancer. In total, 260 patients who underwent complete mesocolic excision for right-sided colon cancer were included in the present analysis. Among the included patients, 69 underwent open radical right-sided colon resection, 175 underwent laparoscopic radical right-sided colon resection and 16 underwent robot-assisted radical right-sided colon resection. The occurrence of PGS was observed, and both the χ test and multivariate regression analysis were conducted to identify influencing factors. Among the 260 patients, 32 experienced PGS, with an incidence rate of 12.3%. Univariate analysis demonstrated that age, perioperative blood glucose levels, self-rated anxiety scale scores and surgical approach were significantly associated with PGS (P<0.05), whereas sex, surgical duration, diabetes and perioperative albumin levels were not significant factors (P>0.05). Multivariate logistic regression analysis showed that age >70 years, perioperative blood glucose ≥11.1 mmol/l, a self-rating anxiety scale score ≥50 and radical extended right-sided colon resection were risk factors for PGS occurrence. In conclusion, the occurrence of PGS in patients with right-sided colon cancer was revealed to be associated with age, perioperative blood glucose levels, self-rated anxiety scale scores and surgical approach.

摘要

本研究旨在探讨影响右侧结肠癌患者术后胃瘫综合征(PGS)的因素。本分析共纳入260例行右侧结肠癌完整结肠系膜切除术的患者。在纳入的患者中,69例行开放性根治性右侧结肠切除术,175例行腹腔镜根治性右侧结肠切除术,16例行机器人辅助根治性右侧结肠切除术。观察PGS的发生情况,并进行χ检验和多因素回归分析以确定影响因素。260例患者中,32例发生PGS,发生率为12.3%。单因素分析表明,年龄、围手术期血糖水平、自评焦虑量表评分和手术方式与PGS显著相关(P<0.05),而性别、手术时间、糖尿病和围手术期白蛋白水平不是显著因素(P>0.05)。多因素logistic回归分析显示,年龄>70岁、围手术期血糖≥11.1 mmol/l、自评焦虑量表评分≥50分和根治性扩大右侧结肠切除术是PGS发生的危险因素。总之,右侧结肠癌患者PGS的发生与年龄、围手术期血糖水平、自评焦虑量表评分和手术方式有关。

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