Yonemura Y, Ooyama S, Ueda N
Gan No Rinsho. 1985 Feb;31(2):162-7.
Ten patients with diffuse multiple glands or cysts in the submucosal layer of the stomach have been extensively studied. The structure of the cyst wall showed two patterns, consisting of monolayer cuboidal or cylindrical cells and pseudoantral or parietal mucosa. All of the multiple cysts were in the submucosal layer under the gastric mucosa with intestinal metaplasia. In these mucosal layers, erosion and ulcer were frequently observed. Four patients had multiple gastric cancers, and the cancers were surrounded by the metaplastic gastric mucosa. We speculated this disorder to be a peculiar regenerative change after gastritis, especially erosion. That repeated erosion and regeneration leads to carcinoma in the stomach with diffuse, heterotopic multiple cysts.
对10例胃黏膜下层有弥漫性多腺体或囊肿的患者进行了广泛研究。囊肿壁结构呈现两种模式，由单层立方或柱状细胞以及假窦或壁细胞黏膜组成。所有多发性囊肿均位于伴有肠化生的胃黏膜下黏膜层。在这些黏膜层中，经常观察到糜烂和溃疡。4例患者患有多发性胃癌，且癌症被化生的胃黏膜所包围。我们推测这种病症是胃炎尤其是糜烂后一种特殊的再生性改变。反复的糜烂和再生导致胃内出现伴有弥漫性、异位性多发性囊肿的癌症。
