Rubio C A, Ohman U
Acta Pathol Microbiol Immunol Scand A. 1982 Sep;90(5):363-6.
Gastrectomy specimens from 51 patients operated on because of peptic ulcer disease were searched histologically for the presence of intramucosal cysts. The number of cysts for each cm of mucosa analyzed (cystic index) was calculated. Intramucosal cysts occurred in 34 per cent of the patients. The resultant cystic index was 0.19 (S.D. +/- 0.40). The cystic index was not correlated to age or sex. Comparative studies demonstrated significantly higher (p less than 0.001) proportions of intramucosal cysts in the non-tumoral mucosa from patients with early gastric cancer (cystic index 3.13 - S.D. +/- 3.55). The possible association between benign intramucosal cystic dilatation of the gastric glands and the occurrence of gastric carcinoma deserves further investigation. The occurrence of intramucosal cysts in a biopsy specimen should intensify the search for an early gastric cancer.
对51例因消化性溃疡疾病接受手术的患者的胃切除标本进行组织学检查，以查找黏膜内囊肿的存在。计算每厘米分析黏膜的囊肿数量（囊性指数）。34%的患者出现黏膜内囊肿。所得囊性指数为0.19（标准差±0.40）。囊性指数与年龄或性别无关。比较研究表明，早期胃癌患者非肿瘤性黏膜中黏膜内囊肿的比例显著更高（p<0.001）（囊性指数3.13 - 标准差±3.55）。胃腺良性黏膜内囊性扩张与胃癌发生之间的可能关联值得进一步研究。活检标本中出现黏膜内囊肿应加强对早期胃癌的排查。
