Zhang Mingyu, Tian Yizhuo, Liu Sijia, Wang Yu, Li Haiyan, Chen Yafei, Gao Qing, Wang Xinli, Chen Mingli
Research Center for Analytical Sciences, Department of Chemistry, College of Sciences, Northeastern University, Shenyang, China.
Analytical and Testing Center, Northeastern University, Shenyang, China.
Luminescence. 2025 Feb;40(2):e70106. doi: 10.1002/bio.70106.
A multifunctional surface-enhanced Raman scattering substrate FeO@AgNPs@MIL-101 was prepared. Rapid SERS detection of pesticide residues was realized by direct pre-enrichment and separation on the peel surface. MIL-101 has an ortho-octahedral framework and large pore size, which endowed FeO@AgNPs@MIL-101 with the ability to rapidly adsorb and separate positively charged targets. The introduction of tannic acid realized the in situ growth of AgNPs on the backbone, to modulate the electromagnetic enhancement. Pesticide molecules were adsorbed onto the surface of AgNPs mediated by central S atoms, accompanied by the interaction between pesticide molecules and AgNPs, the corresponding SERS signals of different pesticides were observed. Together with the introduction of magnetic coating FeO, the molecules were enriched in the hotspot and separated to further enhance the SERS performance. Magnet instead of centrifugation was used to simultaneously perform surface extraction and sample separation for a noninvasive, rapid, immediate, and portable assay. The method was accomplished in measurement of thiram and thiabendazole on apple and tangerine epidermis, and the limits of detection (LODs) were 20 ng/cm and 4 μg/cm, respectively. The recovery was reasonable, and it showed that the procedure is valuable for the rapid and nondestructive surface analysis of residual chemicals.
制备了一种多功能表面增强拉曼散射基底FeO@AgNPs@MIL-101。通过在果皮表面直接预富集和分离实现了对农药残留的快速表面增强拉曼散射检测。MIL-101具有正交八面体骨架和大孔径，这赋予了FeO@AgNPs@MIL-101快速吸附和分离带正电目标物的能力。引入单宁酸实现了AgNPs在骨架上的原位生长，以调节电磁增强。农药分子通过中心S原子介导吸附在AgNPs表面，伴随着农药分子与AgNPs之间的相互作用，观察到了不同农药对应的表面增强拉曼散射信号。再加上引入磁性涂层FeO，分子在热点区域富集并分离，进一步提高了表面增强拉曼散射性能。使用磁铁代替离心进行表面萃取和样品分离，实现了非侵入性、快速、即时和便携式检测。该方法用于苹果和橘子表皮上福美双和噻菌灵的测定，检测限分别为20 ng/cm和4 μg/cm。回收率合理，表明该方法对于残留化学物质的快速无损表面分析具有重要价值。
