Moylan Alice, Brown Jewel, Chen Melissa J, Creinin Mitchell D
University of California, Davis School of Medicine, 4610 X St., Sacramento, CA 95817, USA.
Department of Obstetrics and Gynecology, University of California, Davis Health, 4860 Y Street, Suite 2500, Sacramento, CA 95817, USA.
Case Rep Womens Health. 2025 Jan 17;45:e00687. doi: 10.1016/j.crwh.2025.e00687. eCollection 2025 Mar.
The etonogestrel implant is known to have high contraceptive efficacy for up to 5 years. This case report describes etonogestrel implant failure during year 4 of use in a patient with a normal body mass index. The patient was receiving thyroid hormone replacement after a thyroidectomy and was found to have iatrogenic thyrotoxicosis in the months preceding pregnancy. Further study of the effects of thyroid hormone on etonogestrel metabolism are indicated.
已知依托孕烯植入剂在长达5年的时间内具有较高的避孕效果。本病例报告描述了一名体重指数正常的患者在使用依托孕烯植入剂第4年时避孕失败的情况。该患者在甲状腺切除术后接受甲状腺激素替代治疗，在怀孕前几个月被发现患有医源性甲状腺毒症。有必要进一步研究甲状腺激素对依托孕烯代谢的影响。
