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治疗性营养对颌面部骨折切开复位内固定患者血清白蛋白水平及营养指标影响的比较评估——一项前瞻性临床试验

Comparative Evaluation of Effect of Therapeutic Nutrition on Serum Albumin Levels and Nutritional Indices in Patients Undergoing Open Reduction and Internal Fixation for Maxillofacial Fractures - A Prospective Clinical Trial.

作者信息

Rajanikanth B R, Achar Amruta T, Prasad Kavitha, Arvind Hema

机构信息

Department of Oral and Maxillofacial Surgery, Faculty of Dental Sciences, Ramaiah University of Applied Sciences, Bangalore, 560054 India.

Ramaiah Memorial Hospital, Bangalore, 560054 India.

出版信息

J Maxillofac Oral Surg. 2025 Feb;24(1):110-116. doi: 10.1007/s12663-024-02427-7. Epub 2025 Jan 8.

DOI:10.1007/s12663-024-02427-7
PMID:39902413
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11787073/
Abstract

AIM

To assess effect of therapeutic nutrition on serum albumin levels, nutritional indices and on recovery of patients who have undergone open reduction and internal fixation for maxillofacial fractures.

METHODS

A total of 82 patients were included in this prospective study with 41 patients each in therapeutic and non-therapeutic nutrition group. Pre-operative serum albumin, prognostic nutritional index (PNI) and nutritional risk index (NRI) were calculated. Early wound healing index (EHI) was taken along with serum albumin on day 0 and follow-up day 10 and were compared.

RESULTS

There was statistically significant difference ( < 0.001) between pre- and post-mean serum albumin levels and mean EHI score in both groups. In non-therapeutic group, there was decrease in serum albumin whereas increase in therapeutic group. There was increase in EHI score on follow-up day 10 which indicated improvement in healing in both the groups.

CONCLUSION

Addition of protein supplement increased post-operative serum albumin level. Regardless of type of nutrition, an improvement in healing was seen in both the groups. Special nutrition counselling and care must be given for maxillofacial fracture patients who have additional injuries as this may benefit overall post-operative recovery of the patients.

摘要

目的

评估治疗性营养对接受颌面部骨折切开复位内固定术患者血清白蛋白水平、营养指标及康复情况的影响。

方法

本前瞻性研究共纳入82例患者,治疗性营养组和非治疗性营养组各41例。计算术前血清白蛋白、预后营养指数(PNI)和营养风险指数(NRI)。在第0天和随访第10天测定早期伤口愈合指数(EHI)并与血清白蛋白水平进行比较。

结果

两组患者术前和术后平均血清白蛋白水平及平均EHI评分之间存在统计学显著差异(<0.001)。非治疗组血清白蛋白水平下降,而治疗组升高。随访第10天EHI评分增加,表明两组愈合情况均有改善。

结论

补充蛋白质可提高术后血清白蛋白水平。无论营养类型如何,两组患者的愈合情况均有改善。对于合并其他损伤的颌面部骨折患者,必须给予特殊的营养咨询和护理,因为这可能有利于患者的整体术后康复。

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本文引用的文献

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Effects of Oral Nutritional Supplement on Postoperative Orthognathic Surgery Patients' Nutritional Status: A Randomised Clinical Trial.口服营养补充剂对正颌外科手术患者术后营养状况的影响:一项随机临床试验。
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Nutritional intervention during maxillomandibular fixation of jaw fractures prevents weight loss and improves quality of life.营养干预在颌骨骨折的颌骨固定期间可以防止体重减轻并提高生活质量。
Br J Oral Maxillofac Surg. 2021 May;59(4):478-484. doi: 10.1016/j.bjoms.2020.10.009. Epub 2020 Oct 24.
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What is the role of nutrition counseling in the management of isolated mandible fractures?营养咨询在孤立性下颌骨骨折管理中的作用是什么?
Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Nov;128(5):464-471. doi: 10.1016/j.oooo.2018.12.005. Epub 2018 Dec 14.
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What Is the Effect of Treating Mandibular Fractures on Weight and Prealbumin?治疗下颌骨骨折对体重和前白蛋白有何影响?
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