Ishihara T, Nemoto E, Kikuchi K, Kato R, Kobayashi K
J Thorac Cardiovasc Surg. 1985 May;89(5):665-72.
The effect of bronchial circulation on wound healing at the site of anastomosis after right upper sleeve lobectomy was studied in dogs. In two dogs (Group I), the bronchial arteries were carefully preserved during the sleeve lobectomy. In 16 dogs (Group II), only sleeve lobectomy was performed after all bronchial arteries in the hilum were ligated. In three dogs (Group III), the site of anastomosis was wrapped by a Penrose drain after sleeve lobectomy. In three other dogs (Group IV), the site of anastomosis was wrapped with a free pleural flap after sleeve lobectomy. In another group of 11 dogs (Group V), the anastomotic site was wrapped with a pedicled pleural flap. The dogs in Group I were put to death immediately and bronchial arterial circulation was recognized to consist primarily of systemic arterial blood. In Group II dogs, bronchial arteries distal to the anastomosis filled with pulmonary arterial blood immediately after the sleeve lobectomy. Although the majority of bronchial arteries became filled with systemic arterial blood with time, some vessels were filled with pulmonary arterial blood even 7 days after the sleeve lobectomy. In Group III dogs, wound healing at the site of anastomosis was severely delayed, and 7 days after the sleeve lobectomy the majority of bronchial arteries in the bronchial wall distal to the anastomosis were filled with pulmonary arterial blood. In Group IV dogs, the state of wound healing at the bronchial anastomotic site was similar to that of Group III dogs. In Group V, although the state of wound healing at the anastomosis was relatively good in most of the animals, the pedicled pleural wrap did not significantly improve bronchial circulation over that of Group II.
在犬类动物中研究了支气管循环对右上叶袖状肺叶切除术后吻合口部位伤口愈合的影响。在两只犬（第一组）中，袖状肺叶切除术中仔细保留支气管动脉。在16只犬（第二组）中，肺门处所有支气管动脉结扎后仅进行袖状肺叶切除术。在三只犬（第三组）中，袖状肺叶切除术后用橡皮引流管包裹吻合口部位。在另外三只犬（第四组）中，袖状肺叶切除术后用游离胸膜瓣包裹吻合口部位。在另一组11只犬（第五组）中，用带蒂胸膜瓣包裹吻合口部位。第一组的犬立即处死，发现支气管动脉循环主要由体循环动脉血组成。第二组犬在袖状肺叶切除术后，吻合口远端的支气管动脉立即充满肺动脉血。尽管随着时间推移大多数支气管动脉充满体循环动脉血，但即使在袖状肺叶切除术后7天，仍有一些血管充满肺动脉血。第三组犬吻合口部位的伤口愈合严重延迟，袖状肺叶切除术后7天，吻合口远端支气管壁内的大多数支气管动脉充满肺动脉血。第四组犬支气管吻合口部位的伤口愈合状态与第三组犬相似。在第五组中，尽管大多数动物吻合口部位的伤口愈合状态相对良好，但带蒂胸膜包裹与第二组相比并未显著改善支气管循环。
