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腹腔镜与经皮肾镜激光去顶术治疗单发性肾囊肿的中期疗效比较:一项单中心回顾性研究

Comparison of the mid-term outcomes of laparoscopic and percutaneous nephroscopic laser unroofing for the treatment of single renal cyst: a single-center retrospective study.

作者信息

Tang Zhen, Lu Baode, Zhang Yan, Peng Jiao, Zhao Fenfen, Mo Zengnan

机构信息

Institute of Urology and Nephrology, First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, No. 6, Shuangyong Road, Qingxiu District, Guangxi Zhuang Autonomous Region, Nanning, 530021, Guangxi, China.

Center for Genomic and Personalized Medicine, Guangxi Key Laboratory for Genomic and Personalized Medicine, Guangxi Collaborative Innovation Center for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, 530021, China.

出版信息

Int Urol Nephrol. 2025 Feb 4. doi: 10.1007/s11255-025-04382-9.

Abstract

PURPOSE

Renal cysts are the most common benign disease of the kidneys, and their increasing size cause compression symptoms that require surgical intervention. In this study, we compared the safety, efficacy and prognosis of percutaneous nephroscopic laser unroofing (PNLU) with those of laparoscopic unroofing (LU) for simple renal cysts.

METHODS

Data from patients with single renal cysts who underwent PNLU or LU between Jan 2018 and Dec 2023 were collected and followed up thereafter. Baseline characteristics, perioperative events, blood test results and postoperative complications were compared. Recurrence-free survival (RFS) was also compared via survival analysis. Subgroup analyses were conducted in the PNLU group, including the 980 nm laser and Holmium laser groups.

RESULTS

A total of 75 patients were included, 35 of whom underwent PNLU and 40 of whom underwent LU. Compared with LU, PNLU requires only one surgical incision and is a shorter procedure, causes less blood loss, requires fewer urinary catheter days, is known for quicker drainage tube removal, requires a shorter postoperative hospital stay, has lower hospitalization costs, induces a weaker postoperative inflammatory response, and is associated with a lower incidence of abdominal distension. There was no significant difference in RFS between the PNLU and LU groups. In the subgroup analyses of PNLU, no significant differences were observed between the 980 nm laser and Holmium laser groups.

CONCLUSION

PNLU is safe, effective and cost-effective for single renal cysts and known for a low complication rate, and its mid-term prognosis is similar to that of laparoscopic surgery.

摘要

目的

肾囊肿是最常见的肾脏良性疾病,其体积增大可导致压迫症状,需要手术干预。在本研究中,我们比较了经皮肾镜激光去顶术(PNLU)与腹腔镜去顶术(LU)治疗单纯肾囊肿的安全性、有效性和预后。

方法

收集2018年1月至2023年12月期间接受PNLU或LU治疗的单发性肾囊肿患者的数据,并进行随访。比较基线特征、围手术期事件、血液检查结果和术后并发症。还通过生存分析比较无复发生存率(RFS)。在PNLU组中进行亚组分析,包括980nm激光组和钬激光组。

结果

共纳入75例患者,其中35例接受PNLU治疗,40例接受LU治疗。与LU相比,PNLU仅需一个手术切口,手术时间更短,失血量更少,导尿管留置天数更少,引流管拔除更快,术后住院时间更短,住院费用更低,术后炎症反应更弱,腹胀发生率更低。PNLU组和LU组的RFS无显著差异。在PNLU的亚组分析中,980nm激光组和钬激光组之间未观察到显著差异。

结论

PNLU治疗单发性肾囊肿安全、有效且具有成本效益,并发症发生率低,中期预后与腹腔镜手术相似。

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