Kälin Sonja, Baenziger Julia, Mader Luzius, Harju Erika, Gumy-Pause Fabienne, Niggli Felix, Sommer Grit, Michel Gisela, Roser Katharina
Faculty of Health Sciences and Medicine, University of Lucerne, Lucerne, Switzerland.
Cancer Registry Bern Solothurn, University of Bern, Bern, Switzerland.
Qual Life Res. 2025 Apr;34(4):1079-1090. doi: 10.1007/s11136-025-03892-4. Epub 2025 Feb 4.
Having a child with cancer can profoundly impact parents' health-related quality of life (HRQOL). However, there is a lack of knowledge about the long-term effects of childhood cancer on parents' well-being. The current study aimed to (1) describe the HRQOL of parents of long-term childhood cancer survivors (CCS) and compare it with that of parents from the general population in Switzerland, and (2) investigate sociodemographic and cancer-related determinants of lower HRQOL in parents of CCS.
In this cross-sectional study, a total of 751 parents of CCS (mean time since diagnosis = 23.7 years, SD = 6.7 years) and 454 parents from the general population reported their HRQOL by completing the Short Form-36 (SF-36v2). Sociodemographic and cancer-related characteristics were also collected.
Multilevel regression analyses showed that parents of CCS and parents from the general population had similar physical and mental HRQOL. When comparing mothers and fathers separately, there were no differences between the samples, except for higher HRQOL in the domain of physical functioning in mothers of CCS. Cancer-related characteristics were not associated with HRQOL in parents of CCS. Several sociodemographic characteristics such as being female, being from the French or Italian-speaking part of Switzerland, having a lower education, having a chronic condition, and having a migration background were associated with lower HRQOL.
Parents of CCS are doing well a long time after their child's cancer diagnosis. Nevertheless, tailored support should be provided for at-risk demographic groups.
孩子患癌症会对父母的健康相关生活质量（HRQOL）产生深远影响。然而，对于儿童癌症对父母幸福感的长期影响，我们知之甚少。本研究旨在：（1）描述长期儿童癌症幸存者（CCS）父母的健康相关生活质量，并与瑞士普通人群的父母进行比较；（2）调查CCS父母中健康相关生活质量较低的社会人口学和癌症相关决定因素。
在这项横断面研究中，共有751名CCS父母（诊断后的平均时间=23.7年，标准差=6.7年）和454名普通人群的父母通过填写简明健康调查问卷（SF-36v2）报告了他们的健康相关生活质量。还收集了社会人口学和癌症相关特征。
多层次回归分析表明，CCS父母和普通人群的父母在身体和心理方面的健康相关生活质量相似。分别比较母亲和父亲时，样本之间没有差异，但CCS母亲在身体功能领域的健康相关生活质量较高。癌症相关特征与CCS父母的健康相关生活质量无关。一些社会人口学特征，如女性、来自瑞士法语或意大利语区、教育程度较低、患有慢性病以及有移民背景，与较低的健康相关生活质量有关。
CCS父母在孩子癌症诊断后的很长一段时间里情况良好。然而，应为高危人群提供有针对性的支持。
