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隧道式血液透析导管的长期耐用性:来自单一机构22年经验的结果

Long-Term Durability of Tunneled Hemodialysis Catheters: Outcomes from a Single Institution 22-Year Experience.

作者信息

Zhang Austin, Clark Timothy Wi, Trerotola Scott O

机构信息

Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

Department of Radiology, Division of Interventional Radiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

出版信息

Cardiovasc Intervent Radiol. 2025 May;48(5):619-625. doi: 10.1007/s00270-024-03941-4. Epub 2025 Feb 4.

DOI:10.1007/s00270-024-03941-4
PMID:39904767
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12053159/
Abstract

PURPOSE

To describe long-term physical durability of tunneled hemodialysis catheters, highlighted in the 2019 Kidney Disease Outcomes Quality Initiative (KDOQI) guidelines as a specific area for future research.

MATERIALS AND METHODS

Tunneled hemodialysis catheters with known outcomes and dwell times > 1 year were entered into this retrospective study. Data includes demographics, complications, catheter type, dwell time, reason for removal, access site, and placement via exchange or de novo. Catheter durability < 1 year dwell was analyzed as a secondary aim.

RESULTS

272 catheters in 229 patients were included. Dwell times ranged from 366 to 3,802 days (median 504), totaling 162,439 catheter days. 17 (6%) catheters > 1 year dwell had broken external components. For these, dwell times until breaking ranged from 377 to 1,436 days (median 489), totaling 10,434 catheter days. 5 had a broken hub, 11 had a broken clamp, and 1 had broken hub and clamp. 12 were Ash Split Cath (n = 240) and 5 were Arrow-Clark VectorFlow (n = 32). In the durability < 1 year sub-analysis, 6,515 catheters with dwell times < 1 year in 3,693 patients were included, totaling 425,018 catheter days. 48 were damaged, with 24 broken hubs, 17 broken clamps, and 7 holes. Median time to breakage was 110 days. 38 were Ash Split Cath (n = 5,636) and 10 Arrow-Clark VectorFlow (n = 812). In both analyses, breakage was limited to hubs, clamps, and extensions.

CONCLUSIONS

Tunneled hemodialysis catheters are exceptionally durable, rarely requiring removal for hub-related issues after one year. Breakdown was not observed as a long-term durability issue. Further, broken external components can be replaced using external repair kits.

LEVEL OF EVIDENCE

Level 2b, Retrospective Study.

摘要

目的

描述隧道式血液透析导管的长期物理耐用性,这在2019年《肾脏病预后质量倡议》(KDOQI)指南中被列为未来研究的一个特定领域。

材料与方法

将已知结局且留置时间>1年的隧道式血液透析导管纳入这项回顾性研究。数据包括人口统计学资料、并发症、导管类型、留置时间、拔除原因、穿刺部位以及通过置换或初次置入的放置方式。将留置时间<1年的导管耐用性作为次要目标进行分析。

结果

纳入了229例患者的272根导管。留置时间为366至3802天(中位数为504天),总计162439导管日。17根(6%)留置时间>1年的导管外部部件出现破损。对于这些导管,直至破损的留置时间为377至1436天(中位数为489天),总计10434导管日。5根导管的接头破损,11根导管的夹片破损,1根导管的接头和夹片均破损。12根为灰阶分体导管(n = 240),5根为箭式 - 克拉克矢量流导管(n = 32)。在留置时间<1年的亚组分析中,纳入了3693例患者的6515根留置时间<1年的导管,总计425018导管日。48根导管出现损坏,其中24根接头破损,17根夹片破损,7根有孔洞。破损的中位时间为110天。38根为灰阶分体导管(n = 5636),10根为箭式 - 克拉克矢量流导管(n = 812)。在两项分析中,破损均局限于接头、夹片和延长管。

结论

隧道式血液透析导管具有极高的耐用性,一年后很少因与接头相关的问题而需要拔除。未观察到故障是长期耐用性问题。此外,破损的外部部件可使用外部修复套件进行更换。

证据级别

2b级,回顾性研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c5b2/12053159/5edc7ee0eec2/270_2024_3941_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c5b2/12053159/5edc7ee0eec2/270_2024_3941_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c5b2/12053159/5edc7ee0eec2/270_2024_3941_Fig1_HTML.jpg

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本文引用的文献

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Tunneled Hemodialysis Catheter Insertion: Technical and Clinical Considerations.隧道式血液透析导管插入术:技术与临床考量
Indian J Radiol Imaging. 2022 Dec 7;33(1):76-79. doi: 10.1055/s-0042-1758877. eCollection 2023 Jan.
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Evolutive profile of hemodialysis vascular accesses Hemodialysis accesses.血液透析血管通路的演变过程 血液透析通路。
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Hemodialysis Catheters: Update on Types, Outcomes, Designs and Complications.血液透析导管:类型、结果、设计及并发症的最新进展
Semin Intervent Radiol. 2022 Feb 18;39(1):90-102. doi: 10.1055/s-0042-1742346. eCollection 2022 Feb.
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Arteriovenous Fistula Maturation, Functional Patency, and Intervention Rates.动静脉瘘成熟度、功能通畅率和介入治疗率。
JAMA Surg. 2021 Dec 1;156(12):1111-1118. doi: 10.1001/jamasurg.2021.4527.
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KDOQI Clinical Practice Guideline for Vascular Access: 2019 Update.KDIGO 临床实践指南:血管通路 2019 更新版。
Am J Kidney Dis. 2020 Apr;75(4 Suppl 2):S1-S164. doi: 10.1053/j.ajkd.2019.12.001. Epub 2020 Mar 12.
6
Reasons for long-term tunneled dialysis catheter use and associated morbidity.长期使用隧道式透析导管的原因及相关发病率。
J Vasc Surg. 2021 Feb;73(2):588-592. doi: 10.1016/j.jvs.2020.06.121. Epub 2020 Jul 21.
7
Clinical and Regulatory Considerations for Central Venous Catheters for Hemodialysis.用于血液透析的中心静脉导管的临床和监管注意事项。
Clin J Am Soc Nephrol. 2018 Dec 7;13(12):1924-1932. doi: 10.2215/CJN.14251217. Epub 2018 Oct 11.
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Repair of damaged central venous catheters is safe and doubles catheter survival: a home parenteral nutrition patient cohort study.损伤的中心静脉导管的修复是安全的,可使导管存活率翻倍:一项家庭肠外营养患者队列研究。
Clin Nutr. 2019 Aug;38(4):1692-1699. doi: 10.1016/j.clnu.2018.08.005. Epub 2018 Aug 14.
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J Vasc Access. 2017 Nov 17;18(6):492-497. doi: 10.5301/jva.5000784. Epub 2017 Aug 26.
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Hemodialysis Tunneled Catheter Noninfectious Complications.血液透析带隧道导管非感染性并发症
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