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血液透析血管通路的演变过程 血液透析通路。

Evolutive profile of hemodialysis vascular accesses Hemodialysis accesses.

出版信息

Tunis Med. 2021;99(5):575-581.

PMID:35244908
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8772601/
Abstract

INTRODUCTION

Arterio-venous fistula (AVF) is the first-choice vascular access for hemodialysis (HD). Hemodialysis catheter (KT) may be a temporary or permanent alternative.

AIM

To evaluate indications of KT and AVF and their predictive factors of complications.

METHODS

It's a retrospective multicentric study interesting KT and AVF in patients treated by hemodialysis, in the Kef Governorate in north-western Tunisia, during the period from 01/07/18 to 31/12/18.

RESULTS

We included 288 AVF and 148 KT that were created on 205 patients. The average age was 58.14 years, the sex ratio was 1.5. Hypertensive patients and diabetics represented respectively 83.9% and 27.3% of the population. Diabetic nephropathy was the most common (25.9%). For the KT, the main indication was the wait for AVF creation (68.9%). The overall incidence of immediate complications was 11.5%. Dysfunction was reported in 23.6% of cases with obesity and tunneled type of KT as contributing factors. KT infection was occuring in 39.2% of cases. It was promoted by prolonged duration of use and hemoglobin level < 8g/dl. The use of antiseptic lock reduced infections' risk (p=0.011). For AVF, the most common complications were thrombosis (36.2%), aneurysm (29.9%) and stenosis (22.6%). Survival rate was 60% at 2000 days. The AVF impairing factors were diabetes (p=0.05), obesity (p=0.05), anterior AVF creation (p=0.011), AVF grafts (p=0.016), and anticoagulant therapy (p=0.0001). Antiplatelet therapy improved AVF patency (p=0.02).

CONCLUSION

Much remained to be done to reduce KT complications, creation of AVF on time and prevention of their complications.

摘要

介绍

动静脉瘘(AVF)是血液透析(HD)的首选血管通路。血液透析导管(KT)可能是一种临时或永久的替代方法。

目的

评估 KT 和 AVF 的适应证及其并发症的预测因素。

方法

这是一项回顾性多中心研究,涉及 2018 年 7 月 1 日至 12 月 31 日在突尼斯西北部凯夫省接受血液透析治疗的患者的 KT 和 AVF。

结果

我们纳入了 288 个 AVF 和 148 个 KT,这些 KT 和 AVF 是在 205 名患者身上创建的。平均年龄为 58.14 岁,性别比为 1.5。高血压和糖尿病患者分别占人群的 83.9%和 27.3%。糖尿病肾病是最常见的(25.9%)。对于 KT,主要适应证是等待 AVF 创建(68.9%)。总的即时并发症发生率为 11.5%。功能障碍的发生与肥胖和隧道型 KT 有关,其发生率为 23.6%。KT 感染发生率为 39.2%。延长使用时间和血红蛋白水平<8g/dl 会促进感染。使用抗菌锁可降低感染风险(p=0.011)。对于 AVF,最常见的并发症是血栓形成(36.2%)、动脉瘤(29.9%)和狭窄(22.6%)。2000 天时的生存率为 60%。影响 AVF 的因素是糖尿病(p=0.05)、肥胖(p=0.05)、前 AVF 构建(p=0.011)、AVF 移植物(p=0.016)和抗凝治疗(p=0.0001)。抗血小板治疗可改善 AVF 通畅率(p=0.02)。

结论

仍需努力减少 KT 并发症、及时创建 AVF 并预防其并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1977/8772601/fdc68ae82cd2/fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1977/8772601/b03e503098f1/fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1977/8772601/fdc68ae82cd2/fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1977/8772601/b03e503098f1/fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1977/8772601/fdc68ae82cd2/fig2.jpg

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