Chen Hongzhou, Li Mengyuan, Li Tian, Chen Mai, Jiang Chao, Tang Yudian, Chen Qian, Cheng Dazhi
School of Psychology, Capital Normal University, 100073, Beijing, China.
State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, 100875, Beijing, China.
Sci Data. 2025 Feb 4;12(1):207. doi: 10.1038/s41597-025-04531-w.
Recent studies have highlighted the potential association between common benign epilepsy syndromes in children and the development of partial cognitive impairment. We established a comprehensive database of cognitive, structural magnetic resonance imaging (sMRI), and resting-state functional magnetic resonance imaging (rsfMRI) data obtained from a cohort of 36 Chinese paediatric volunteers. The participants, aged 5-16 years, were specifically diagnosed with either benign epilepsy with centrotemporal spikes (BECTs) or childhood absence epilepsy by certified paediatric neurologists. All imaging data were collected by qualified clinicians, and cognitive data were collected within 1 year of magnetic resonance imaging data collection. This database allows researchers to perform more detailed analyses using multimodal data to explore the relationship between cognitive impairment and brain mechanisms in children with common epilepsy syndromes.
近期研究突显了儿童常见良性癫痫综合征与部分认知障碍发展之间的潜在关联。我们建立了一个综合数据库，其中包含从36名中国儿科志愿者队列中获取的认知、结构磁共振成像（sMRI）和静息态功能磁共振成像（rsfMRI）数据。参与者年龄在5至16岁之间，由认证的儿科神经科医生明确诊断为伴有中央颞区棘波的良性癫痫（BECTs）或儿童失神癫痫。所有成像数据均由合格的临床医生收集，认知数据在磁共振成像数据收集的1年内收集。该数据库使研究人员能够使用多模态数据进行更详细的分析，以探索常见癫痫综合征儿童认知障碍与脑机制之间的关系。
