Velagic Vedran, Pasara Vedran, Prepolec Ivan, Nekic Andrija, Katic Zvonimir, Milicic Davor
Department of Cardiovascular Diseases, University of Zagreb School of Medicine, University Hospital Centre Zagreb, Kišpatićeva 12, 10000, Zagreb, Croatia.
Sci Rep. 2025 Feb 4;15(1):4280. doi: 10.1038/s41598-025-87940-6.
We aimed to investigate the feasibility and safety of zero-fluoro approach for the repeat atrial fibrillation (AF) procedures after initial cryoballoon (CB) ablation. We have performed a retrospective study on patients that have undergone repeat pulmonary vein isolation (PVI) procedures in our institution since zero-fluoro program was initiated in 2020. All patients received CB ablation for the initial procedure. Repeat procedures were performed under conscious sedation and with intracardiac echo (ICE) and 3D mapping system - without the use of fluoroscopy and lead aprons. We have analysed in total 50 patients (76% male, 57.9 ± 10.2 years old), 50% of which suffered from paroxysmal AF. All procedures were successfully performed without the use of fluoroscopy. The mean procedure time was 93.9 ± 27.1 min and the mean RF time was 825 ± 468 s. The mean of 0.98 ± 0.91 veins was reconnected per patient and 36% of patients did not have PV reconnections. In all patients successful PV isolation was performed, confirmed by entry and exit block. No major periprocedural complications were observed. After the mean follow up of 12.5 ± 3.4 months: 68% of mixed AF population patients were free from AF after one year. In our cohort of patients, zero-fluoro, apron-less approach for repeat PVI procedures after index cryoballoon ablation proved to be feasible and safe. Index CB ablation resulted with low rates of PV reconnections and mid-term results after repeat procedures are favourable.
我们旨在研究在初次冷冻球囊(CB)消融后,采用零射线方法进行复发性心房颤动(AF)手术的可行性和安全性。自2020年启动零射线计划以来,我们对在本机构接受复发性肺静脉隔离(PVI)手术的患者进行了一项回顾性研究。所有患者初次手术均接受CB消融。复发性手术在清醒镇静下进行,并使用心内超声(ICE)和三维标测系统,不使用荧光透视和铅衣。我们总共分析了50例患者(男性占76%,年龄57.9±10.2岁),其中50%患有阵发性AF。所有手术均在不使用荧光透视的情况下成功完成。平均手术时间为93.9±27.1分钟,平均射频时间为825±468秒。每位患者平均重新连接0.98±0.91条静脉,36%的患者没有肺静脉重新连接。所有患者均成功实现肺静脉隔离,通过入口和出口阻滞得到证实。未观察到主要的围手术期并发症。平均随访12.5±3.4个月后:68%的混合型AF患者在一年后无AF发作。在我们的患者队列中,初次冷冻球囊消融后采用零射线、无铅衣方法进行复发性PVI手术被证明是可行和安全的。初次CB消融导致肺静脉重新连接率较低,复发性手术后的中期结果良好。