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基于压电陶瓷电压和振动频率的高强度聚焦超声对组织热效应加热规律的研究

Study on the heating law of thermal effect of HIFU on tissue based on piezoelectric ceramic voltage and vibration frequency.

作者信息

Long Yuping, Gan Yi, Sun Fujia, Zhao Yansong

机构信息

School of Mechanical Engineering, University of Shanghai for Science and Technology, Shanghai, China.

出版信息

Sci Rep. 2025 Feb 4;15(1):4168. doi: 10.1038/s41598-025-87166-6.

DOI:10.1038/s41598-025-87166-6
PMID:39905147
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11794541/
Abstract

When high-intensity focused ultrasound (HIFU) is used to heat human tissues during surgery, shortening the heating time and increasing the heating rate are crucial for implementing surgery. During operations, the vibration frequencies and voltages that are suitable for piezoelectric ceramics can maximize the heating rate of HIFU. To correctly select the frequency and voltage of piezoelectric ceramics, it is necessary to understand the change law between the frequency and voltage of piezoelectric ceramics and the temperature of the heated tissue. Therefore, this study focuses on the piezoelectric ceramics in the ultrasonic transducer that produces HIFU. By coupling the piezoelectric equation, Helmholtz equation, and biological heat transfer equation of piezoelectric ceramics, the solid mechanical properties of piezoelectric ceramics and the sound field and temperature field produced by its vibration are combined to determine the influence of vibration frequency and voltage on heating time. Results show that the relation between the temperature variation of the tissue, vibration frequency, and voltage of the piezoelectric ceramics can be determined using the Rational Taylor function. The maximum voltage that the piezoelectric ceramics with different frequencies can withstand varies greatly.

摘要

在手术中使用高强度聚焦超声(HIFU)加热人体组织时,缩短加热时间和提高加热速率对于实施手术至关重要。在手术过程中,适合压电陶瓷的振动频率和电压能够使HIFU的加热速率最大化。为了正确选择压电陶瓷的频率和电压,有必要了解压电陶瓷的频率和电压与被加热组织温度之间的变化规律。因此,本研究聚焦于产生HIFU的超声换能器中的压电陶瓷。通过耦合压电陶瓷的压电方程、亥姆霍兹方程和生物传热方程,将压电陶瓷的固体力学性能与其振动产生的声场和温度场相结合,以确定振动频率和电压对加热时间的影响。结果表明,组织温度变化与压电陶瓷振动频率和电压之间的关系可用有理泰勒函数确定。不同频率的压电陶瓷所能承受的最大电压差异很大。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e337/11794541/570b5453e55d/41598_2025_87166_Fig10_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e337/11794541/a3d0dc96ebb8/41598_2025_87166_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e337/11794541/570b5453e55d/41598_2025_87166_Fig10_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e337/11794541/a17eeabaf499/41598_2025_87166_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e337/11794541/460da9413ee3/41598_2025_87166_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e337/11794541/45ba2d85e221/41598_2025_87166_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e337/11794541/3791436e69a1/41598_2025_87166_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e337/11794541/901abe852a28/41598_2025_87166_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e337/11794541/49ed44e7ab27/41598_2025_87166_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e337/11794541/10148d526af1/41598_2025_87166_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e337/11794541/78216867ba75/41598_2025_87166_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e337/11794541/a3d0dc96ebb8/41598_2025_87166_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e337/11794541/570b5453e55d/41598_2025_87166_Fig10_HTML.jpg

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