Lee Albert S T, Tong Ching Man Carmen
Division of Urology, Texas Children's Hospital, Houston, USA.
Department of Urology, Baylor College of Medicine, Houston, USA.
Curr Urol Rep. 2025 Feb 5;26(1):26. doi: 10.1007/s11934-025-01256-6.
Near-infrared fluorescence imaging (NIRF) with the use of indocyanine green (ICG) has been recently adopted in pediatric urology after its well-published use in the adult population. As a powerful tool that can help delineate complex anatomy and congenital anomalies, we discuss the various applications of this imaging in minimally invasive and open surgery in pediatric urology.
The most reported applications of ICG in pediatric urology are within minimally invasive surgery, particularly varicoceles, renal surgery such as nephrectomies and renal tumor excision, mimicking its use in adult urology. ICG has also been applied to reconstructive urology such as ureteral reconstruction, hypospadias repair and bladder exstrophy. Despite its safety and more widespread use in pediatric surgery, all published studies in pediatric urology to date have been limited to small and single-center experiences, reflecting the novel nature of this technology in this field. ICG has been shown to be safe and effective in children, particularly in those with complex anatomy and in technically challenging surgeries. Future studies should focus on standardized protocols for children and multi-center comparative studies.
使用吲哚菁绿（ICG）的近红外荧光成像（NIRF）在成人群体中广泛应用后，最近已被儿科泌尿外科采用。作为一种有助于描绘复杂解剖结构和先天性异常的有力工具，我们讨论这种成像在儿科泌尿外科微创手术和开放手术中的各种应用。
ICG在儿科泌尿外科中报道最多的应用是在微创手术中，特别是精索静脉曲张、肾手术如肾切除术和肾肿瘤切除，这与它在成人泌尿外科中的应用类似。ICG也已应用于重建泌尿外科，如输尿管重建、尿道下裂修复和膀胱外翻。尽管其安全性高且在儿科手术中应用更为广泛，但迄今为止儿科泌尿外科所有已发表的研究都局限于小规模单中心经验，这反映了该技术在该领域的新颖性。ICG已被证明在儿童中安全有效，特别是在那些解剖结构复杂和手术技术具有挑战性的儿童中。未来的研究应侧重于针对儿童的标准化方案和多中心比较研究。
