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[地塞米松治疗与未治疗的严重颅脑创伤的治疗结果]

[Treatment results in severe craniocerebral trauma with and without dexamethasone therapy].

作者信息

Sollmann W P, Hussein S, Stolke D

出版信息

Neurochirurgia (Stuttg). 1985 Mar;28(2):46-50. doi: 10.1055/s-2008-1054182.

DOI:10.1055/s-2008-1054182
PMID:3990889
Abstract

A retrospective study was performed to determine the effect of dexamethasone-therapy on the outcome of severe head injuries not combined with other serious injuries. Between 1981 and 1983 we treated 53 of 110 patients with an initial dose of 40 mg dexamethasone followed by 16 mg daily for 10 days. There was no statistically significant difference in the outcome and the lethality of the steroid and nonsteroid group. Infections or other complications did not occur more frequent in dexamethasone-therapy.

摘要

进行了一项回顾性研究,以确定地塞米松治疗对未合并其他严重损伤的重度颅脑损伤预后的影响。1981年至1983年间,我们对110例患者中的53例进行了治疗,初始剂量为40毫克地塞米松,随后每天16毫克,持续10天。类固醇组和非类固醇组在预后和致死率方面没有统计学上的显著差异。地塞米松治疗中感染或其他并发症的发生频率并未更高。

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[Treatment results in severe craniocerebral trauma with and without dexamethasone therapy].[地塞米松治疗与未治疗的严重颅脑创伤的治疗结果]
Neurochirurgia (Stuttg). 1985 Mar;28(2):46-50. doi: 10.1055/s-2008-1054182.
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[Possibilities and limitations of intensive therapy in severe craniocerebral injuries].[重症颅脑损伤强化治疗的可能性与局限性]
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"Ultrahigh" dexamethasone in acute brain injury. Results from a prospective randomized double-blind multicenter trial (GUDHIS). German Ultrahigh Dexamethasone Head Injury Study Group.急性脑损伤中的“超高剂量”地塞米松。一项前瞻性随机双盲多中心试验(GUDHIS)的结果。德国超高剂量地塞米松脑损伤研究组
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Prognosis of severe head injuries in childhood and adolescence.儿童和青少年重度颅脑损伤的预后
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[Ultra-high, short-term dexamethasone therapy in craniocerebral trauma. Rationale and design of a multicenter study].[超短期大剂量地塞米松治疗颅脑创伤。一项多中心研究的理论依据与设计]
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