Sollmann W P, Hussein S, Stolke D
Neurochirurgia (Stuttg). 1985 Mar;28(2):46-50. doi: 10.1055/s-2008-1054182.
A retrospective study was performed to determine the effect of dexamethasone-therapy on the outcome of severe head injuries not combined with other serious injuries. Between 1981 and 1983 we treated 53 of 110 patients with an initial dose of 40 mg dexamethasone followed by 16 mg daily for 10 days. There was no statistically significant difference in the outcome and the lethality of the steroid and nonsteroid group. Infections or other complications did not occur more frequent in dexamethasone-therapy.
进行了一项回顾性研究,以确定地塞米松治疗对未合并其他严重损伤的重度颅脑损伤预后的影响。1981年至1983年间,我们对110例患者中的53例进行了治疗,初始剂量为40毫克地塞米松,随后每天16毫克,持续10天。类固醇组和非类固醇组在预后和致死率方面没有统计学上的显著差异。地塞米松治疗中感染或其他并发症的发生频率并未更高。