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双眼和单眼遮挡对含有退化细胞器的视神经轴突数量的影响。

The effects of binocular and monocular occlusion on the number of optic nerve axons containing degenerative organelles.

作者信息

Ehrlich D, Mills D

出版信息

Neurosci Lett. 1985 Mar 15;54(2-3):351-6.

PMID:3991073
Abstract

In this study chicks were incubated in the dark and then reared for 2 days with either none, one or both eyes occluded. Cross-sections of the optic nerves were examined for profiles of axons containing accumulations of degenerative organelles. There were significantly more organelle-containing axons in the non-occluded and monocularly occluded birds compared with the binocularly occluded birds. There was no significant difference between the non-occluded and monocular group. Furthermore, there was no significant difference between the occluded and non-occluded eyes of monocular birds. We propose that the rise in organelle-containing axons during development reflects a phenomenon involved in the linking of the eyes, and that visual input to a single eye is sufficient to hasten this process.

摘要

在本研究中,雏鸡在黑暗中孵化,然后在双眼均不遮挡、单眼遮挡或双眼都遮挡的条件下饲养2天。检查视神经的横截面,以观察含有退行性细胞器聚集物的轴突轮廓。与双眼遮挡的雏鸡相比,未遮挡和单眼遮挡的雏鸡中含有细胞器的轴突明显更多。未遮挡组和单眼遮挡组之间没有显著差异。此外,单眼雏鸡的遮挡眼和未遮挡眼之间也没有显著差异。我们认为,发育过程中含有细胞器的轴突数量增加反映了一种与双眼连接有关的现象,并且单眼的视觉输入足以加速这一过程。

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Neurosci Lett. 1985 Mar 15;54(2-3):351-6.
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