Borges Marcio Vinícius Campos, Pereira Erika Martins, Santos Raysa Theresa Pinheiro, de Oliveira Izabel Cristina Vieira, Thomaz Erika Barbara Abreu Fonseca, Rodrigues Vandilson
Dentistry Graduate Program, Federal University of Maranhão, São Luís, Brazil.
Department of Basic and Oral Biology, University of Sao Paulo School of Dentistry, Ribeirão Preto, Brazil.
J Public Health Dent. 2025 Mar;85(1):102-110. doi: 10.1111/jphd.12658. Epub 2025 Feb 5.
This study investigated regional trends in delays between the histological diagnosis of oral and oropharyngeal cancer and initiation of treatment across Brazil's federal units from 2013 to 2019.
A retrospective, observational study was conducted using secondary data from the Brazilian Health System Database (DATASUS) for the years 2013-2019. Variables collected included the year of treatment, sex, age group, anatomical location, disease stage, treatment method, and federal unit of Brazil. Thematic maps were generated, and time series were analyzed using joint-point regression.
A total of 72,062 cases were included in the study. Majority of cases were of men (79.32%) and individuals older than 45 years (91.15%). Treatment was initiated earlier in younger patients, in cases of lip cancer, and among those who had undergone surgery. In 11 states, a significant decrease was observed in initiating treatment for oral cancer 60 days from diagnosis, whereas a significant increase was observed in three states. For oropharyngeal cancer, a significant decrease was observed in initiating treatment at 60 days from diagnosis in three states, whereas a significant increase was observed in five states.
The findings revealed a high degree of heterogeneity in treatment delays for oral and oropharyngeal cancer across Brazil from 2013 to 2019. The northern states of Brazil exhibited a high percentage of treatment delays exceeding 60 days.
本研究调查了2013年至2019年巴西各联邦单位口腔和口咽癌组织学诊断与治疗开始之间延迟的区域趋势。
利用巴西卫生系统数据库（DATASUS）2013 - 2019年的二手数据进行了一项回顾性观察研究。收集的变量包括治疗年份、性别、年龄组、解剖位置、疾病阶段、治疗方法以及巴西的联邦单位。绘制了专题地图，并使用联合点回归分析了时间序列。
该研究共纳入72,062例病例。大多数病例为男性（79.32%）以及年龄超过45岁的个体（91.15%）。年轻患者、唇癌患者以及接受过手术的患者治疗开始时间较早。在11个州，确诊后60天内开始口腔癌治疗的情况显著减少，而在3个州则显著增加。对于口咽癌，3个州确诊后60天内开始治疗的情况显著减少，而在5个州则显著增加。
研究结果显示，2013年至2019年巴西口腔和口咽癌治疗延迟存在高度异质性。巴西北部各州治疗延迟超过60天的比例很高。
