Hong Yujeong, Kim Hyojung, Lee Dong-Hee
Department of Otolaryngology-Head and Neck Surgery, The Catholic University of Korea, Seoul, Korea.
J Audiol Otol. 2025 Jan;29(1):67-74. doi: 10.7874/jao.2024.00311. Epub 2025 Jan 20.
Wernicke encephalopathy, also known as thiamine deficiency, is characterized by a triad of symptoms: ophthalmoplegia, ataxia, and confusion. However, additional symptoms may manifest depending on the area affected by the lesion. Although multiple cranial neuropathies are possible, sudden onset bilateral hearing loss has been described in rare situations as the first manifestation of Wernicke encephalopathy. Here, we present a case report detailing the clinical experience of a patient diagnosed with Wernicke encephalopathy, whose initial presentation included sudden bilateral deafness. The patient was a 57-year-old man with alcoholism who was successfully diagnosed with Wernicke encephalopathy, and his hearing improved after high-dose intravenous thiamine therapy. Our case study results and a literature review indicate that video findings and suppression head impulse tests can be used to evaluate Wernicke encephalopathy.
韦尼克脑病,也称为硫胺素缺乏症,其特征为三联征症状:眼肌麻痹、共济失调和精神错乱。然而,根据病变所影响的区域,可能会出现其他症状。虽然可能出现多种颅神经病变,但在罕见情况下,突发双侧听力丧失已被描述为韦尼克脑病的首发表现。在此,我们报告一例详细的临床病例,该患者被诊断为韦尼克脑病,其最初表现为突发双侧耳聋。患者为一名57岁的酗酒男性,成功诊断为韦尼克脑病,大剂量静脉注射硫胺素治疗后听力改善。我们的病例研究结果和文献综述表明,视频检查结果和摇头抑制试验可用于评估韦尼克脑病。