Morgan Zackquill J, Cler Leslie, Hunter Leigh
Internal Medicine, Methodist Dallas Medical Center, Dallas, TX, USA.
J Community Hosp Intern Med Perspect. 2020 Sep 3;10(5):443-445. doi: 10.1080/20009666.2020.1808359.
We report the case of a 46-year old African American woman who presented to the emergency department with one week of progressive bilateral deafness associated with worsening gait abnormalities, visual changes, and confusion. She was diagnosed with Wernicke encephalopathy (WE) attributed to alcohol abuse; her symptoms, including hearing loss, improved with thiamine replacement. WE, a condition due to thiamine deficiency, commonly affects those with alcohol use disorder or gastric bypass history. Though traditionally associated with a triad of encephalopathy, ophthalmoplegia, and ataxia, it can be more rarely associated with auditory deficits or other neurologic findings. Though hearing loss has previously been reported as a rare symptom of WE, it has not been described in WE due to alcohol abuse. We performed a review of the literature to determine if WE associated with hearing loss had been previously reported.
我们报告了一例46岁的非裔美国女性病例，该患者因进行性双侧耳聋伴步态异常加重、视力变化和意识模糊一周而就诊于急诊科。她被诊断为韦尼克脑病（WE），病因是酒精滥用；补充硫胺素后，她包括听力丧失在内的症状有所改善。WE是一种由硫胺素缺乏引起的疾病，通常影响有酒精使用障碍或胃旁路手术史的人群。虽然传统上与脑病、眼肌麻痹和共济失调三联征相关，但它很少与听觉缺陷或其他神经系统表现相关。虽然听力丧失此前已被报道为WE的罕见症状，但尚未在因酒精滥用导致的WE中描述过。我们对文献进行了回顾，以确定此前是否有关于与听力丧失相关的WE的报道。
