Xu Kai, Li Ya-Ling, Xiao Song-Hua, Pan Yong-Wei
Department of Orthopedics, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
J Int Med Res. 2025 Feb;53(2):3000605251315300. doi: 10.1177/03000605251315300.
OBJECTIVE: This study aimed to evaluate the therapeutic effects of minimally invasive lateral, posterior, and posterolateral sacroiliac joint fusion for low back pain through a meta-analysis. METHODS: The PubMed, Web of Science, Embase, Cochrane Library, and ClinicalTrials.gov databases were comprehensively searched for studies up to 31 August 2024. Relevant studies using lateral, posterior, and posterolateral approaches were identified. Pooled outcomes and publication bias were assessed. The study was registered with PROSPERO (registration No. CRD42023451047). RESULTS: A total of 48 studies were included: 32 focused on the lateral approach, 10 on the posterior approach, four on the posterolateral approach, and two compared the lateral and posterolateral approaches. The pooled effect analysis showed statistically significant improvements in the visual analog scale (VAS) scores for all three approaches at 6 and 12 months postoperatively. Although no between-approach comparisons were conducted, the pooled improvements in VAS scores at 6 and 12 months postoperatively were numerically similar across all three approaches, as were the pooled fusion rates. The pooled complication rate for the lateral approach was 9.2%, numerically higher than 1% for the posterior approach. The pooled revision rate for the lateral approach was 2.4%, also numerically higher than 0.6% for the posterior approach. CONCLUSIONS: Although pain relief and fusion rates were similar across all approaches, the lateral approach might be associated with a higher risk of total complications and revision surgery.
目的:本研究旨在通过荟萃分析评估微创外侧、后侧和后外侧骶髂关节融合术治疗腰痛的疗效。 方法:全面检索了截至2024年8月31日的PubMed、Web of Science、Embase、Cochrane图书馆和ClinicalTrials.gov数据库中的研究。确定了使用外侧、后侧和后外侧入路的相关研究。评估汇总结果和发表偏倚。该研究已在PROSPERO注册(注册号CRD42023451047)。 结果:共纳入48项研究:32项聚焦于外侧入路,10项聚焦于后侧入路,4项聚焦于后外侧入路,2项比较了外侧和后外侧入路。汇总效应分析显示,所有三种入路术后6个月和12个月时视觉模拟量表(VAS)评分均有统计学意义的改善。尽管未进行入路间比较,但所有三种入路术后6个月和12个月时VAS评分的汇总改善情况在数值上相似,汇总融合率也是如此。外侧入路的汇总并发症发生率为9.2%,在数值上高于后侧入路的1%。外侧入路的汇总翻修率为2.4%,在数值上也高于后侧入路的0.6%。 结论:尽管所有入路的疼痛缓解和融合率相似,但外侧入路可能与更高的总体并发症和翻修手术风险相关。
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