Bourre J M, Chanez C, Dumont O, Durand G, Faivre A, Nouvelot A, Pascal G, Piciotti M
Reprod Nutr Dev (1980). 1985;25(1B):335-40.
Polyunsaturated fatty acids, especially omega 3 fatty acids, made a specific contribution to the nervous tissue. Retarded intrauterine growth caused a twofold reduction in the oligodendrocyte ratio of omega 3/omega 6 while the same ratio increased by more than twofold in the neurons. A fatty acid-poor diet composed of arachid or sunflower oil dramatically altered the composition of cells and subcellular particles when compared with a soya or rapeseed oil diet containing omega 3 fatty acids; phosphatidylethanolamine was particularly affected. Nerve cell culture showed that brain essential fatty acids are probably docosahexaenoic acid and arachidonic acid.
多不饱和脂肪酸，尤其是ω-3脂肪酸，对神经组织有特殊贡献。子宫内生长迟缓导致少突胶质细胞中ω-3/ω-6的比例降低了两倍，而神经元中的同一比例则增加了两倍多。与含有ω-3脂肪酸的大豆油或菜籽油饮食相比，由花生油或向日葵油组成的低脂肪酸饮食显著改变了细胞和亚细胞颗粒的组成；磷脂酰乙醇胺受到的影响尤为明显。神经细胞培养表明，大脑必需脂肪酸可能是二十二碳六烯酸和花生四烯酸。
