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Possible interrelations of acetyl-homocysteine-thiolactone in mechanisms of lipofuscinogenesis.

作者信息

Aloj Totaro E, Pisanti F A, Liberatori E

出版信息

Res Commun Chem Pathol Pharmacol. 1985 Mar;47(3):415-26.

PMID:3992017
Abstract

The administration of acetyl-homocysteine-thiolactone (cythiolone) to Torpedo marmorata inhibits the production of neuronal lipofuscin. The possible mechanism of this action has been investigated. A free radical scavenger effect of the drug has been demonstrated both in vivo and in vitro. Cythiolone is able to activate the enzyme superoxide dismutase, while no effect has been detected on catalase activity.

摘要

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引用本文的文献

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Effect of acetylhomocysteine thiolactone on nucleolar cytology and lipofuscinogenesis in electric lobe neurons.
Experientia. 1988 Aug 15;44(8):712-3. doi: 10.1007/BF01941039.
2
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Diabetologia. 1989 Nov;32(11):792-6. doi: 10.1007/BF00264909.
3
Protection by free oxygen radical scavenging enzymes against glucose-induced embryonic malformations in vitro.体外实验中自由基清除酶对葡萄糖诱导的胚胎畸形的保护作用。
Diabetologia. 1991 May;34(5):325-31. doi: 10.1007/BF00405004.