Bayou Fekade Demeke, Arefaynie Mastewal, Mohammed Anissa, Tareke Abiyu Abadi, Keleb Awoke, Kebede Natnael, Tsega Yawkal, Mersha Bayu Hailemariam, Endawkie Abel, Kebede Shimels Derso, Abera Kaleab Mesfin, Abeje Eyob Tilahun, Enyew Ermias Bekele, Daba Chala, Asmare Lakew
Department of Epidemiology and Biostatistics, School of Public Health, College of Medicine and Health Science, Wollo University, Dessie, Ethiopia.
Department of Reproductive and Family Health, School of Public Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.
Ital J Pediatr. 2025 Feb 7;51(1):32. doi: 10.1186/s13052-025-01838-7.
Respiratory tract infection (RTI) has been a predominant health problem worldwide, including Ethiopia. It is one of the major causes of under-five mortality in Ethiopia, accountable for 18% of total deaths. Nationwide studies on the incidence of respiratory infections and maternal risk factors are limited. Hence, this study was aimed to determine the incidence and predictors of respiratory infections among infants aged less than six months in Ethiopia, 2023.
This was a retrospective follow up study using data from Performance Monitoring for Action Ethiopia (PMA Ethiopia). A two-stage cluster sampling technique was used to select a total 2,246 eligible study participants from 206 enumeration areas. A Cox proportional hazards regression model was used to identify independent predictors of respiratory tract infection incidence. Hazard ratios with 95% confidence intervals and p value < 0.05 were used to declare statically significant associations between variables.
The incidence rate of respiratory tract infections among birth cohorts was 22.99 per 1000 infant weeks of observation. Infants born from mothers who sustained convulsion during labor had nearly doubled [AHR = 1.65, 95%CI (1.20, 2.28)] hazard or risk of developing respiratory tract infections than their counterparts. Similarly, infants born from mothers having prolonged labor (more than 12 h) had one and half times [AHR = 1.48, 95%CI (1.13, 1.93)] increased risk of developing respiratory tract infections as compared to their counterparts.
The incidence of respiratory tract infections is a significant public health concern in Ethiopia. Infants born to mothers with prolonged labor and convulsions need closer monitoring for early signs of respiratory tract infections.
包括埃塞俄比亚在内,呼吸道感染(RTI)一直是全球主要的健康问题。它是埃塞俄比亚五岁以下儿童死亡的主要原因之一,占总死亡人数的18%。关于呼吸道感染发病率和孕产妇风险因素的全国性研究有限。因此,本研究旨在确定2023年埃塞俄比亚六个月以下婴儿呼吸道感染的发病率及预测因素。
这是一项回顾性随访研究,使用来自埃塞俄比亚行动绩效监测(PMA Ethiopia)的数据。采用两阶段整群抽样技术,从206个普查区域中总共选取2246名符合条件的研究参与者。使用Cox比例风险回归模型来确定呼吸道感染发病率的独立预测因素。采用95%置信区间的风险比和p值<0.05来表明变量之间具有统计学意义的关联。
出生队列中呼吸道感染的发病率为每1000个婴儿观察周22.99例。分娩时母亲发生抽搐的婴儿发生呼吸道感染的风险或几率几乎是其他婴儿的两倍[AHR = 1.65,95%CI(1.20,2.28)]。同样,与其他婴儿相比,母亲分娩时间延长(超过12小时)的婴儿发生呼吸道感染的风险增加了1.5倍[AHR = 1.48,95%CI(1.13,1.93)]。
呼吸道感染的发病率是埃塞俄比亚一个重大的公共卫生问题。分娩时间延长和发生抽搐的母亲所生的婴儿需要密切监测呼吸道感染的早期迹象。