Essman E J
Ric Clin Lab. 1985 Jan-Mar;15(1):19-24. doi: 10.1007/BF03029157.
Pulmonary alveolar macrophages harvested from the albino mouse lung were shown to possess surface receptor sites capable of binding physiological concentrations of serotonin (5-hydroxytryptamine). These specific, high affinity binding sites showed temperature-dependent kinetics with a single order high affinity binding site for serotonin. The presence of serotonin receptors on pulmonary alveolar macrophages provides a basis for relating at least one mediator of pulmonary inflammatory processes and transport processes to effects upon the macrophage surface.
从白化小鼠肺中收获的肺泡巨噬细胞被证明具有能够结合生理浓度血清素（5-羟色胺）的表面受体位点。这些特异性的高亲和力结合位点表现出温度依赖性动力学，对血清素具有单一的高亲和力结合位点。肺泡巨噬细胞上血清素受体的存在为将肺部炎症过程和转运过程的至少一种介质与对巨噬细胞表面的影响联系起来提供了基础。
