Mirotti L, Castro J, Costa-Pinto F A, Russo M
Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, Brazil.
J Allergy (Cairo). 2010;2010:491928. doi: 10.1155/2010/491928. Epub 2011 Feb 9.
Allergy is on the rise worldwide. Asthma, food allergy, dermatitis, and systemic anaphylaxis are amongst the most common allergic diseases. The association between allergy and altered behavior patterns has long been recognized. The molecular and cellular pathways in the bidirectional interactions of nervous and immune systems are now starting to be elucidated. In this paper, we outline the consequences of allergic diseases, especially food allergy and asthma, on behavior and neural activity and on the neural modulation of allergic responses.
过敏在全球范围内呈上升趋势。哮喘、食物过敏、皮炎和全身性过敏反应是最常见的过敏性疾病。过敏与行为模式改变之间的关联早已为人所知。神经和免疫系统双向相互作用中的分子和细胞途径现在开始得到阐明。在本文中,我们概述了过敏性疾病,尤其是食物过敏和哮喘,对行为和神经活动以及过敏反应的神经调节的影响。