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儿童化脓性汗腺炎疾病特征的种族差异

Racial Differences in Disease Characteristics of Pediatric Hidradenitis Suppurativa.

作者信息

Onamusi Toluwalashe, Murphy Jennifer, Shah Sonal D

机构信息

Department of Dermatology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.

Department of Dermatology, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.

出版信息

Pediatr Dermatol. 2025 Feb 9;42(4):806-9. doi: 10.1111/pde.15891.

Abstract

Understanding the potential racial differences in presentation, severity, and outcomes of pediatric hidradenitis suppurativa (HS) can help deliver equitable and individualized care, especially as this condition is increasingly being acknowledged in this population. We conducted a single-center retrospective analysis of 70 pediatric patients diagnosed with HS who were seen at our institution. There was no statistically significant difference in biologic treatments between non-Hispanic Black (NHB) patients when compared to non-Hispanic White (NHW) patients, although NHW patients overall received biologic therapy more frequently (17.4%) than NHB patients (12.8%). The observed racial differences in pediatric HS highlight the need for further investigation of possible underlying factors contributing to disease heterogeneity and treatment response to optimize the care provided and patient outcomes.

摘要

了解儿童化脓性汗腺炎(HS)在表现、严重程度和预后方面的潜在种族差异,有助于提供公平且个性化的护理,尤其是鉴于这种疾病在该人群中越来越受到认可。我们对在我们机构就诊的70例诊断为HS的儿科患者进行了单中心回顾性分析。与非西班牙裔白人(NHW)患者相比,非西班牙裔黑人(NHB)患者在生物治疗方面没有统计学上的显著差异,尽管NHW患者总体上比NHB患者更频繁地接受生物治疗(17.4%对12.8%)。在儿童HS中观察到的种族差异凸显了进一步调查可能导致疾病异质性和治疗反应的潜在因素的必要性,以优化所提供的护理和患者预后。

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Hidradenitis suppurativa in pediatric patients.儿童化脓性汗腺炎
J Am Acad Dermatol. 2022 Jan;86(1):140-147. doi: 10.1016/j.jaad.2020.08.045. Epub 2020 Aug 18.
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Biologic therapies for the treatment of hidradenitis suppurativa.生物疗法治疗化脓性汗腺炎。
Expert Opin Biol Ther. 2020 Jun;20(6):621-633. doi: 10.1080/14712598.2020.1732918. Epub 2020 Mar 6.

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