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儿童化脓性汗腺炎疾病特征的种族差异

Racial Differences in Disease Characteristics of Pediatric Hidradenitis Suppurativa.

作者信息

Onamusi Toluwalashe, Murphy Jennifer, Shah Sonal D

机构信息

Department of Dermatology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.

Department of Dermatology, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.

出版信息

Pediatr Dermatol. 2025 Feb 9;42(4):806-9. doi: 10.1111/pde.15891.

DOI:10.1111/pde.15891
PMID:39924924
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12285565/
Abstract

Understanding the potential racial differences in presentation, severity, and outcomes of pediatric hidradenitis suppurativa (HS) can help deliver equitable and individualized care, especially as this condition is increasingly being acknowledged in this population. We conducted a single-center retrospective analysis of 70 pediatric patients diagnosed with HS who were seen at our institution. There was no statistically significant difference in biologic treatments between non-Hispanic Black (NHB) patients when compared to non-Hispanic White (NHW) patients, although NHW patients overall received biologic therapy more frequently (17.4%) than NHB patients (12.8%). The observed racial differences in pediatric HS highlight the need for further investigation of possible underlying factors contributing to disease heterogeneity and treatment response to optimize the care provided and patient outcomes.

摘要

了解儿童化脓性汗腺炎(HS)在表现、严重程度和预后方面的潜在种族差异,有助于提供公平且个性化的护理,尤其是鉴于这种疾病在该人群中越来越受到认可。我们对在我们机构就诊的70例诊断为HS的儿科患者进行了单中心回顾性分析。与非西班牙裔白人(NHW)患者相比,非西班牙裔黑人(NHB)患者在生物治疗方面没有统计学上的显著差异,尽管NHW患者总体上比NHB患者更频繁地接受生物治疗(17.4%对12.8%)。在儿童HS中观察到的种族差异凸显了进一步调查可能导致疾病异质性和治疗反应的潜在因素的必要性,以优化所提供的护理和患者预后。

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本文引用的文献

1
Characteristics and treatment pathways in pediatric and adult hidradenitis suppurativa: An examination using real world data.儿童及成人化脓性汗腺炎的特征与治疗途径:基于真实世界数据的研究
JAAD Int. 2023 May 30;12:124-132. doi: 10.1016/j.jdin.2023.05.011. eCollection 2023 Sep.
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Pediatric hidradenitis suppurativa: Describing care patterns in the emergency department.小儿化脓性汗腺炎:描述急诊科的护理模式。
Pediatr Dermatol. 2023 May-Jun;40(3):434-439. doi: 10.1111/pde.15231. Epub 2023 Mar 1.
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Real-World Findings on the Characteristics and Treatment Exposures of Patients with Hidradenitis Suppurativa from US Claims Data.基于美国索赔数据的化脓性汗腺炎患者特征及治疗暴露情况的真实世界研究结果
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African American race is a risk factor for severe hidradenitis suppurativa.非裔美国人种是化脓性汗腺炎严重程度的一个风险因素。
Int J Dermatol. 2023 May;62(5):657-663. doi: 10.1111/ijd.16428. Epub 2022 Oct 2.
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Hidradenitis suppurativa in patients of color is associated with increased disease severity and healthcare utilization: A retrospective analysis of 2 U.S. cohorts.有色人种患者的化脓性汗腺炎与疾病严重程度增加及医疗资源利用增加相关:对两个美国队列的回顾性分析。
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Hidradenitis suppurativa in pediatric patients.儿童化脓性汗腺炎
J Am Acad Dermatol. 2022 Jan;86(1):140-147. doi: 10.1016/j.jaad.2020.08.045. Epub 2020 Aug 18.
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Expert Opin Biol Ther. 2020 Jun;20(6):621-633. doi: 10.1080/14712598.2020.1732918. Epub 2020 Mar 6.
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Prevalence Estimates for Hidradenitis Suppurativa among Children and Adolescents in the United States: A Gender- and Age-Adjusted Population Analysis.美国儿童和青少年化脓性汗腺炎的患病率估计:一项性别和年龄调整的人口分析。
J Invest Dermatol. 2018 Oct;138(10):2152-2156. doi: 10.1016/j.jid.2018.04.001. Epub 2018 Apr 13.
9
Sex- and Age-Adjusted Population Analysis of Prevalence Estimates for Hidradenitis Suppurativa in the United States.美国化脓性汗腺炎患病率估计值的性别和年龄调整人口分析。
JAMA Dermatol. 2017 Aug 1;153(8):760-764. doi: 10.1001/jamadermatol.2017.0201.
10
Comorbidities of hidradenitis suppurativa (acne inversa).化脓性汗腺炎(反向性痤疮)的合并症。
Dermatoendocrinol. 2010 Jan;2(1):9-16. doi: 10.4161/derm.2.1.12490.