Campos-Cunha João, Martins João B, Carneiro Gonçalo, Maia Helena
Internal Medicine, Centro Hospitalar de Entre Douro e Vouga, Santa Maria da Feira, PRT.
Cureus. 2025 Jan 10;17(1):e77242. doi: 10.7759/cureus.77242. eCollection 2025 Jan.
Catecholamine-producing tumours are rare entities that, even though their clinical diagnostic might be a challenge due to the non-specificity of the symptoms, have had a growing incidence due to the continuous improvement of medical imaging examinations and the evolution of molecular genetic testing. On the other hand, they can rarely manifest as serious complications, such as myocardial infarction, stroke, or alveolar haemorrhage. This paper describes the case of a 77-year-old Caucasian man who presented with acute onset of left upper quadrant abdominal pain. The first abdominal computed tomography (CT) scan showed an active haemorrhage originating from a retroperitoneal paraganglioma. The patient received intravenous fluids and prothrombin complex concentrate for reversal of anticoagulation therapy. A reassessment CT scan performed 12 hours later suggested increased bleeding, and laboratory findings showed a worsening of the anemia, so an angiography was performed which didn't show any evidence of haemorrhage. After a multidisciplinary discussion, it was decided to admit the patient for surveillance and imaging evaluation. Six days later, a second reassessment CT showed signs of haemorrhagic resolution, and the patient was discharged with subsequent follow-up in the outpatient clinic. The authors highlight this case for being a rare complication of an equally rare neuroendocrine tumour.
产生儿茶酚胺的肿瘤是罕见的实体瘤,尽管由于症状的非特异性,其临床诊断可能具有挑战性,但由于医学影像检查的不断改进和分子基因检测的发展,其发病率一直在上升。另一方面,它们很少表现为严重并发症,如心肌梗死、中风或肺泡出血。本文描述了一名77岁白种男性患者,其以左上腹急性腹痛为表现。首次腹部计算机断层扫描(CT)显示出血源自腹膜后副神经节瘤。患者接受静脉输液和凝血酶原复合物浓缩物以逆转抗凝治疗。12小时后进行的重新评估CT扫描提示出血增加,实验室检查结果显示贫血加重,因此进行了血管造影,但未显示任何出血迹象。经过多学科讨论,决定收治患者进行监测和影像评估。六天后,第二次重新评估CT显示出血消退迹象,患者出院,随后在门诊进行随访。作者强调该病例是一种同样罕见的神经内分泌肿瘤的罕见并发症。