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小儿下腹部手术中腰方肌阻滞与腹横肌平面阻滞的术后镇痛效果:一项系统评价和荟萃分析

Postoperative Analgesic Effects of Quadratus Lumborum Block Versus Transversus Abdominis Plane Block in Pediatric Lower Abdominal Surgeries: A Systematic Review and Meta-Analysis.

作者信息

Aldalati Abdullah Yousef, Hussein Ayham Mohammad, Ataya Raghad, Alrabadi Bassel, Odat Ramez M, Idrees Muhammad, Al-Dabagh Ahmad, Kamal Zaid, Aloudat Osama, Al-Qaoud Ahmad

机构信息

Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.

Faculty of Medicine, Al-Balqa' Applied University, Salt, Jordan.

出版信息

J Pain Res. 2025 Feb 4;18:567-577. doi: 10.2147/JPR.S502044. eCollection 2025.

DOI:10.2147/JPR.S502044
PMID:39926192
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11806731/
Abstract

OBJECTIVE

Management of postoperative pain in pediatric patients is challenging. Traditional methods of postoperative pain management may not always provide adequate relief. We aim to compare the effect of Quadratus Lumborum Block (QLB) and Transversus Abdominis Plane Block (TAPB) on the quality of postoperative analgesia in pediatrics undergoing lower abdominal surgeries.

METHODS

We systematically searched PubMed, Scopus, Web of Science, and Cochrane Library up to August 2024 for studies that compared QLB and TAPB in the context of pediatric lower abdominal surgery. Pooled mean difference (MD), standardized mean difference (SMD), and odds ratio (OR) were calculated by a random effect model using RevMan 5.4.

RESULTS

Nine studies met the pre-defined inclusion criteria. Pooled analysis indicated that postoperative pain measured by the FLACC score was lower in the QLB group compared to the TAPB group (MD: -0.37; 95% CI: -0.51, -0.23; P < 0.00001). QLB was also associated with lower rescue analgesic demand (OR: 0.25; 95% CI, 0.13, 0.49; P < 0.0001), higher parent satisfaction (SMD: 0.78; 95% CI: 0.53, 1.02; P < 0.00001), longer time without the need for analgesic administration (MD: 1.04; 95% CI: 0.38, 1.71; P = 0.002), and lower paracetamol consumption (SMD: -1.40; 95% CI: -2.43, -0.36; P = 0.008). However, no significant difference was found in terms of postoperative nausea, vomiting, and heart rate.

CONCLUSION

QLB provides superior analgesia compared to TAPB in pediatrics undergoing lower abdominal surgeries.

摘要

目的

小儿患者术后疼痛的管理具有挑战性。传统的术后疼痛管理方法可能并不总能提供充分的缓解。我们旨在比较腰方肌阻滞(QLB)和腹横肌平面阻滞(TAPB)对接受下腹部手术的儿科患者术后镇痛质量的影响。

方法

我们系统检索了截至2024年8月的PubMed、Scopus、Web of Science和Cochrane图书馆,以查找在儿科下腹部手术背景下比较QLB和TAPB的研究。使用RevMan 5.4通过随机效应模型计算合并平均差(MD)、标准化平均差(SMD)和比值比(OR)。

结果

九项研究符合预先定义的纳入标准。汇总分析表明,与TAPB组相比,QLB组通过FLACC评分测量的术后疼痛更低(MD:-0.37;95%CI:-0.51,-0.23;P<0.00001)。QLB还与更低的补救性镇痛需求相关(OR:0.25;95%CI,0.13,0.49;P<0.0001)、更高的家长满意度(SMD:0.78;95%CI:0.53,1.02;P<0.00001)、更长的无需镇痛给药时间(MD:1.04;95%CI:0.38,1.71;P = 0.002)以及更低的对乙酰氨基酚消耗量(SMD:-1.40;95%CI:-2.43,-0.36;P = 0.008)。然而,在术后恶心、呕吐和心率方面未发现显著差异。

结论

在接受下腹部手术的儿科患者中,与TAPB相比,QLB提供了更好的镇痛效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eaff/11806731/76cd77f08981/JPR-18-567-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eaff/11806731/6434960cfb54/JPR-18-567-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eaff/11806731/daf0cb0d136a/JPR-18-567-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eaff/11806731/988418f2bd39/JPR-18-567-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eaff/11806731/6bad4ebc9afb/JPR-18-567-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eaff/11806731/76cd77f08981/JPR-18-567-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eaff/11806731/6434960cfb54/JPR-18-567-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eaff/11806731/daf0cb0d136a/JPR-18-567-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eaff/11806731/988418f2bd39/JPR-18-567-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eaff/11806731/6bad4ebc9afb/JPR-18-567-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eaff/11806731/76cd77f08981/JPR-18-567-g0005.jpg

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