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多种支气管胸膜瘘通过联合支架治疗得以解决。

Multiple bronchopleural fistulas resolved with combination stent therapy.

作者信息

Jimu Aga, Liu Xiuli, Fan Yingqi, Yu Pengfei

机构信息

Department of Respiratory and Critical Care Medicine, Yantai Yuhuangding Hospital, Yantai, China.

出版信息

Ann Thorac Med. 2025 Jan-Mar;20(1):82-85. doi: 10.4103/atm.atm_101_24. Epub 2024 Oct 23.

DOI:10.4103/atm.atm_101_24
PMID:39926396
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11804959/
Abstract

Bronchopleural fistula (BPF) is a rare yet severe complication following lobectomy, with no standardized treatment protocol established. We present a case of a 65-year-old male with chronic obstructive pulmonary disease who developed multiple BPFs postresection of the right lower lobe due to lung cancer and with tumor recurrence and metastasis. We employed a comprehensive management strategy comprising rigorous infection control, meticulous chest drainage, antitumor treatment, and targeted deployment of bronchial stents. This approach not only resolved the BPFs but also achieved a complete response of the lung cancer, extending progression-free survival to over 3 years.

摘要

支气管胸膜瘘(BPF)是肺叶切除术后一种罕见但严重的并发症,目前尚无标准化的治疗方案。我们报告一例65岁男性慢性阻塞性肺疾病患者,因肺癌行右下叶切除术后发生多处BPF,并伴有肿瘤复发和转移。我们采用了一种综合管理策略,包括严格的感染控制、细致的胸腔引流、抗肿瘤治疗以及有针对性地置入支气管支架。这种方法不仅解决了BPF问题,还使肺癌获得了完全缓解,将无进展生存期延长至3年以上。

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本文引用的文献

1
Risk factors for bronchopleural fistula based on surgical procedure and sex in 4794 consecutive patients undergoing anatomical pulmonary resection.4794 例行解剖性肺切除术患者中基于手术方式和性别的支气管胸膜瘘风险因素。
Surg Today. 2024 Jun;54(6):617-626. doi: 10.1007/s00595-023-02761-2. Epub 2023 Nov 4.
2
Prevalence and treatment outcome of bronchopleural fistula: a multi-center study in Ethiopia.支气管胸膜瘘的患病率和治疗结局:埃塞俄比亚的一项多中心研究。
J Cardiothorac Surg. 2023 Jul 12;18(1):227. doi: 10.1186/s13019-023-02325-y.
3
Bronchoscopic interventions for bronchopleural fistulas.
支气管镜介入治疗支气管胸膜瘘。
Ther Adv Respir Dis. 2023 Jan-Dec;17:17534666231164541. doi: 10.1177/17534666231164541.
4
A novel technique for Endobronchial Watanabe Spigot placement for bronchopleural fistula: a traction method.一种用于支气管胸膜瘘的支气管腔内 Watanabe Spigot 放置的新方法:牵引法。
Eur J Cardiothorac Surg. 2021 Nov 2;60(5):1237-1238. doi: 10.1093/ejcts/ezab332.
5
Modified silicone stent for the treatment of post-surgical bronchopleural fistula: a clinical observation of 17 cases.改良型硅胶支架治疗术后支气管胸膜瘘 17 例临床观察。
BMC Pulm Med. 2021 Jan 6;21(1):10. doi: 10.1186/s12890-020-01372-8.
6
Bronchopleural Fistula in the Mechanically Ventilated Patient: A Concise Review.机械通气患者的支气管胸膜瘘:简要综述。
Crit Care Med. 2021 Feb 1;49(2):292-301. doi: 10.1097/CCM.0000000000004771.
7
Bronchopleural Fistula Closure With Amplatzer Device: Our Case and Reviewing a Decade of Experience.使用Amplatzer装置闭合支气管胸膜瘘:我们的病例及十年经验回顾
J Bronchology Interv Pulmonol. 2020 Jul;27(3):e41-e45. doi: 10.1097/LBR.0000000000000637.
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Endoscopic closure of a bronchopleural fistula after pneumonectomy with the Amplatzer occluder: a step forward?使用Amplatzer封堵器进行肺切除术后支气管胸膜瘘的内镜封堵:向前迈进了一步?
Interact Cardiovasc Thorac Surg. 2020 Feb 1;30(2):249-254. doi: 10.1093/icvts/ivz241.
9
Endoscopic and surgical treatment for bronchopleural fistula after major lung resection: an enduring challenge.肺大切除术后支气管胸膜瘘的内镜及手术治疗:一项长期挑战。
J Thorac Dis. 2019 May;11(Suppl 9):S1351-S1356. doi: 10.21037/jtd.2019.03.102.