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经导管主动脉瓣置换术后瓣周漏相关溶血性贫血的经皮治疗

Percutaneous Management of Paravalvular Leak-Related Hemolytic Anemia After Transcatheter Aortic Valve Replacement.

作者信息

Idowu Abiodun, Witzke Christian

机构信息

Department of Medicine, Jefferson Einstein Hospital, Philadelphia, USA.

Division of Interventional Cardiology, Jefferson Einstein Hospital, Philadelphia, USA.

出版信息

Eur J Case Rep Intern Med. 2025 Jan 27;12(2):005138. doi: 10.12890/2025_005138. eCollection 2025.

DOI:10.12890/2025_005138
PMID:39926565
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11801517/
Abstract

UNLABELLED

We present a case of a patient with severe intravascular hemolytic anemia from a paravalvular leak after transcatheter aortic valve replacement and describe a technique of percutaneous repair of the leak with a vascular plug that resolved the patient's transfusion-dependent hemolysis.

LEARNING POINTS

Paravalvular leak after transcatheter aortic valve replacement could lead to intractable hemolytic anemia.Percutaneous paravalvular leak repair with vascular plug implantation is a feasible treatment for aortic prosthesis leak-related hemolysis.

摘要

未标注

我们报告了一例经导管主动脉瓣置换术后因瓣周漏导致严重血管内溶血的患者，并描述了一种使用血管封堵器经皮修复漏口的技术，该技术解决了患者依赖输血的溶血问题。

学习要点

经导管主动脉瓣置换术后的瓣周漏可导致难治性溶血性贫血。植入血管封堵器经皮修复瓣周漏是治疗与主动脉假体漏相关溶血的一种可行方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeaa/11801517/ca2aa28f3978/5138_Fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeaa/11801517/ae6d66f88038/5138_Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeaa/11801517/2af040727a62/5138_Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeaa/11801517/4dd38d9a892e/5138_Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeaa/11801517/81b928408df8/5138_Fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeaa/11801517/ca2aa28f3978/5138_Fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeaa/11801517/ae6d66f88038/5138_Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeaa/11801517/2af040727a62/5138_Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeaa/11801517/4dd38d9a892e/5138_Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeaa/11801517/81b928408df8/5138_Fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeaa/11801517/ca2aa28f3978/5138_Fig5.jpg

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本文引用的文献

1
2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.2020 ACC/AHA 瓣膜性心脏病患者管理指南：执行摘要：美国心脏病学会/美国心脏协会联合临床实践指南委员会的报告。
Circulation. 2021 Feb 2;143(5):e35-e71. doi: 10.1161/CIR.0000000000000932. Epub 2020 Dec 17.
2
Transcatheter and Surgical Management of Mitral Paravalvular Leak: Long-Term Outcomes.经导管和手术治疗二尖瓣瓣周漏：长期结果。
JACC Cardiovasc Interv. 2017 Oct 9;10(19):1946-1956. doi: 10.1016/j.jcin.2017.07.046.
3
Paravalvular aortic leak after transcatheter aortic valve replacement: current knowledge.
经导管主动脉瓣置换术后瓣周主动脉瓣反流：当前认知
Circulation. 2013 Jan 22;127(3):397-407. doi: 10.1161/CIRCULATIONAHA.112.142000.
4
Impact of residual regurgitation after aortic valve replacement.主动脉瓣置换术后残余反流的影响。
Eur J Cardiothorac Surg. 2012 Sep;42(3):486-92. doi: 10.1093/ejcts/ezs083. Epub 2012 Mar 16.
5
Early and late results of the surgical correction of cardiac prosthetic paravalvular leaks.心脏人工瓣膜瓣周漏手术矫正的早期和晚期结果
J Heart Valve Dis. 2005 Nov;14(6):792-9; discussion 799-800.