Sheikh Junaid Zafar, Lunjani Nonhlanhla, Gul Hira, Kila Louay, Casserly Brian
Respiratory Medicine, University Hospital Limerick, Limerick, Ireland.
APC Microbiome Ireland, University College Cork, Cork, Ireland.
Eur J Case Rep Intern Med. 2025 Jan 7;12(2):004963. doi: 10.12890/2025_004963. eCollection 2025.
is a rare cause of non-tuberculous mycobacterial infection in adults, primarily affecting the immunocompromised. Pulmonary involvement has been seen in individuals with pre-existing lung pathology. We report a case of a 63-year-old female who presented with abdominal pain, cough and sputum samples yielding , with a normal clinical examination. Initial investigations were unremarkable, prompting abdomen and pelvis computed tomography (CT), revealing minimal pericardial and ascitic fluid. Thoracic CT exhibited calcified tree-in-bud nodules and a trivial left pleural effusion. Given subdued symptoms and limited disease, discerning colonisation versus clinically relevant infection was uncertain. Due to lack of empirical data for guidance, treatment approaches at this juncture remain unclear. The patient was monitored closely for a period of one year with a plan to treat should there be evidence of active disease.
This case demonstrated an atypical presentation of rare non-tuberculous Mycobacterium.Whether the case involves infection or colonisation needs to be distinguished.There is limited utility of clinical diagnostic algorithms for non-tuberculous mycobacteria in .
是成人非结核分枝杆菌感染的罕见原因，主要影响免疫功能低下者。在已有肺部病变的个体中可见肺部受累。我们报告一例63岁女性，表现为腹痛、咳嗽，痰标本培养出[具体结果未给出]，临床检查正常。初步检查无异常，遂行腹部和盆腔计算机断层扫描（CT），显示心包和腹水极少。胸部CT显示有钙化的树芽状结节和少量左侧胸腔积液。鉴于症状不明显且疾病范围有限，难以确定是定植还是临床相关感染。由于缺乏经验数据指导，此时的治疗方法仍不明确。对患者进行了为期一年的密切监测，如有活动性疾病证据则计划进行治疗。
该病例展示了罕见非结核分枝杆菌的非典型表现。需要区分该病例是感染还是定植。临床诊断算法对非结核分枝杆菌在[具体情况未明确]中的应用有限。
