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一道小伤口,一个大挑战:意外宿主中的儿童毛霉菌病

A Small Cut, a Big Challenge: Pediatric Mucormycosis in an Unexpected Host.

作者信息

Tanvir Marriam, Tanvir Ali, Khan Saad, Henna Fathimathul, Fatima Syeda Mashal, Munir Aqsa, Iqbal Javed

机构信息

Khawaja Muhammad Safdar Medical College Sialkot Punjab Pakistan.

King Edward Medical University Neela Gumbad Lahore Punjab Pakistan.

出版信息

Clin Case Rep. 2025 Feb 7;13(2):e70176. doi: 10.1002/ccr3.70176. eCollection 2025 Feb.

Abstract

Mucormycosis is an infrequent fungal infection commonly seen in immunocompromised individuals. However, it can also occur in immunocompetent patients, especially following trauma. We present a case of a 15-month-old girl with increasing swelling and redness in her left eye after a minor traumatic injury. Imaging showed sinusitis with orbital involvement. Histopathology validated the diagnosis of mucormycosis caused by Rhizopus species. The patient had emergency surgery, followed by antifungal and antibiotic therapy. Despite febrile reactions to the treatment, the infection was managed, and the patient was discharged after 2 months. This case highlights the importance of considering mucormycosis in immunocompetent patients with unexplained ocular symptoms after trauma. Early diagnosis and aggressive treatment are essential for improving outcomes, especially in pediatric patients.

摘要

毛霉菌病是一种罕见的真菌感染,常见于免疫功能低下的个体。然而,它也可发生在免疫功能正常的患者中,尤其是在创伤后。我们报告一例15个月大女童,在轻微外伤后左眼肿胀和发红加重。影像学检查显示鼻窦炎伴眼眶受累。组织病理学证实为根霉属引起的毛霉菌病。患者接受了急诊手术,随后进行了抗真菌和抗生素治疗。尽管治疗过程中出现发热反应,但感染得到了控制,患者在2个月后出院。该病例强调了在免疫功能正常的创伤后出现不明原因眼部症状的患者中考虑毛霉菌病的重要性。早期诊断和积极治疗对于改善预后至关重要,尤其是在儿科患者中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8dd/11805715/d7b70a5d411e/CCR3-13-e70176-g003.jpg

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