Kothari Ruchi, Vrindavanam Suryadev A, Emandi Alekhya, Vakamullu Rashmita, Kanthamneni Mohana, Vemparala Sai S
Department of Physiology, Mahatma Gandhi Institute of Medical Science Sevagram, Wardha, Maharashtra, India.
Internal Medicine, Alluri Sita Ramaraju Academy of Medical Sciences, Eluru, Andhra Pradesh, India.
J Pharm Bioallied Sci. 2024 Dec;16(Suppl 4):S3559-S3561. doi: 10.4103/jpbs.jpbs_1042_24. Epub 2024 Oct 30.
Hypertension is a leading risk factor for cardiovascular diseases, and its impact on cardiorespiratory fitness is significant. This study aims to compare the cardiorespiratory responses to treadmill exercise between healthy adults and hypertensive individuals to evaluate the fitness differences between these two groups.
This case-control study included 100 participants, 50 hypertensive patients, and 50 age- and sex-matched healthy controls. All participants underwent a standardized treadmill exercise test, during which heart rate, blood pressure, and oxygen consumption (VO2 max) were measured. The primary outcomes were the differences in heart rate response, systolic blood pressure, and VO2 max between the two groups.
The hypertensive group exhibited significantly higher resting heart rates and systolic blood pressure than the healthy controls ( < 0.01). During exercise, hypertensives showed a blunted heart rate response and lower VO2 max, indicating reduced cardiorespiratory fitness. Recovery time post-exercise was also prolonged in the hypertensive group ( < 0.05).
The study highlights significant differences in cardiorespiratory fitness between healthy adults and hypertensive individuals. Hypertensives demonstrate reduced exercise capacity, emphasizing the need for targeted interventions to improve cardiovascular health in this population.
高血压是心血管疾病的主要危险因素,其对心肺适能的影响显著。本研究旨在比较健康成年人与高血压患者在跑步机运动时的心肺反应,以评估这两组人群的适能差异。
本病例对照研究纳入了100名参与者,其中50名高血压患者以及50名年龄和性别匹配的健康对照者。所有参与者均接受了标准化的跑步机运动测试,在此期间测量心率、血压和耗氧量(最大摄氧量)。主要结局指标为两组之间心率反应、收缩压和最大摄氧量的差异。
高血压组的静息心率和收缩压显著高于健康对照组(<0.01)。运动期间,高血压患者的心率反应迟钝且最大摄氧量较低,表明心肺适能降低。高血压组运动后的恢复时间也延长(<0.05)。
该研究突出了健康成年人与高血压患者在心肺适能方面的显著差异。高血压患者表现出运动能力下降,强调了针对该人群进行改善心血管健康的针对性干预的必要性。