Nicolson T B, Nettleton P F, Spence J A, Calder K H
Vet Rec. 1985 Mar 16;116(11):281-4. doi: 10.1136/vr.116.11.281.
In 1980, 16 abortions or stillbirths occurred and 26 deformed calves were born in a beef herd of 115 Friesian cross Hereford cows mated to Charolais bulls. The deformities were principally arthrogryposes with contractures, particularly of the forelimbs, and various skull abnormalities. Following investigation it was considered highly unlikely that hereditary causes, infectious agents or a nutritional deficiency were responsible. The most likely cause was exposure to an unidentified teratogen early in pregnancy.
1980年,在一个由115头弗里生杂交赫里福德母牛与夏洛来公牛交配的肉牛群中,发生了16例流产或死产,并有26头畸形小牛出生。畸形主要为关节弯曲并伴有挛缩,尤其是前肢,以及各种颅骨异常。经过调查,认为遗传性病因、传染因子或营养缺乏不太可能是导致这些情况的原因。最可能的原因是在怀孕早期接触了一种不明致畸剂。