Department of Otolaryngology-Head and Neck Surgery, Korea University College of Medicine, Goryeodae-ro, Seongbuk-gu, Seoul, 02841, South Korea.
Department of Statistics and Actuarial Science, Soongsil University, Seoul, South Korea.
Sci Rep. 2020 Jul 9;10(1):11356. doi: 10.1038/s41598-020-67799-5.
The aim of this study was to estimate the total number and rate of chronic otitis media (COM) operations and cholesteatoma surgeries in South Korea, using a nationwide survey which analysed a 13-year trend (2006-2018). This study also analysed the trend of COM operations and cholesteatoma surgeries according to year, sex, and age using a nationwide population-based database, and the 13-year trend was analysed according to age groups. This study used nationwide data from the National Health Information Database (NHID), which is a government-affiliated agency under the Korean Ministry of Health and Welfare that supervises all medical activities in Korea. Retrospective medical data of patients of all ages were extracted from the NHID from January 2006 to December 2018 (NHIS-2018). This study was conducted by the Research Committee of the Korean Society of Otorhinolaryngology-Head and Neck Surgery, and the Korean Audiological Society reviewed and confirmed the study. There was a 1.5 fold increase in COM operation rates in 2018, compared to 2007 figures. The annual total number of COM operations was 5,935 in 2007, 8,999 in 2012 (peak), and 8,870 in 2018 (17 in 100,000). Meanwhile, the total annual number of cholesteatoma surgeries decreased from 3,502 in 2006 to 3,199 in 2018 (6 in 100,000). The rate of COM operations was higher (1.27 fold) in the female population than in the males in 2018. However, cholesteatoma surgery rates were higher (1.2 fold) in the male population than in the females in 2018. According to the 2018 data, COM operations were most commonly performed in patients in their 50s. COM operation rates increased rapidly in patients aged 51-80. In other age groups however, rates were constant or showed a decrease in figures, especially in the 40s age group (1st rank in 2006 to 3rd rank in 2018). According to the 2018 data, cholesteatoma surgery was most commonly performed in patients in their 50s. Cholesteatoma surgery rates increased dramatically from 2006 to 2018 in patients aged 0-10 years due to congenital cholesteatoma. Cholesteatoma surgery rates also increased in patients aged 61-80 years due to ageing population. Cholesteatoma surgery rates decreased in patients aged 41-50 years, ranking 1st in 2006 and 4th in 2018. In conclusion, the annual rate of COM operations was 0.017%, and no longer increases, but stabilizes/decreased after a peak point in the advanced country. The mean rate of cholesteatoma surgery was 0.006%, and decreased annually. There was female dominance in COM operations, but male dominance in cholesteatoma surgery. Major age groups of patients who underwent COM/cholesteatoma surgery were the 50s and 60s, and congenital cholesteatoma (0-10 years) accounted for about 20% of all cholesteatoma surgery.
本研究旨在利用一项全国性调查分析 13 年趋势（2006-2018 年），估算韩国慢性中耳炎（COM）手术和胆脂瘤手术的总数和比率。本研究还使用全国人口为基础的数据库，根据年、性别和年龄分析 COM 手术和胆脂瘤手术的趋势，并根据年龄组分析 13 年的趋势。本研究使用了国家健康信息数据库（NHID）的全国数据，NHID 是隶属于韩国保健福利部的一个政府机构，负责监督韩国所有的医疗活动。从 2006 年 1 月至 2018 年 12 月（NHIS-2018），从 NHID 中提取了所有年龄段患者的回顾性医疗数据。本研究由韩国耳鼻喉科学会研究委员会进行，韩国听力学学会审查并确认了该研究。与 2007 年相比，2018 年 COM 手术率增加了 1.5 倍。2007 年 COM 手术总数为 5935 例，2012 年（峰值）为 8999 例，2018 年为 8870 例（每 10 万人中有 17 例）。与此同时，2006 年胆脂瘤手术总数为 3502 例，2018 年减少至 3199 例（每 10 万人中有 6 例）。2018 年女性的 COM 手术率（1.27 倍）高于男性，但男性的胆脂瘤手术率（1.2 倍）高于女性。根据 2018 年的数据，COM 手术最常见于 50 多岁的患者。51-80 岁患者的 COM 手术率迅速增加。然而，在其他年龄组中，比率保持不变或呈下降趋势，尤其是在 40 多岁年龄组（2006 年排名第一，2018 年排名第三）。根据 2018 年的数据，胆脂瘤手术最常见于 50 多岁的患者。由于先天性胆脂瘤，0-10 岁患者的胆脂瘤手术率从 2006 年到 2018 年急剧增加。由于人口老龄化，61-80 岁患者的胆脂瘤手术率也有所增加。41-50 岁患者的胆脂瘤手术率下降，2006 年排名第一，2018 年排名第四。总之，COM 手术的年发病率为 0.017%，在发达国家达到峰值后不再增加，但趋于稳定或下降。胆脂瘤手术的平均发病率为 0.006%，呈逐年下降趋势。COM 手术以女性为主，但胆脂瘤手术以男性为主。接受 COM/胆脂瘤手术的主要年龄组为 50 多岁和 60 多岁，先天性胆脂瘤（0-10 岁）占所有胆脂瘤手术的约 20%。
