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[在巴特哈尔健康度假村为期4周的停留期间,饮食、运动和碘浴疗法对糖尿病患者血液流变学参数影响的比较研究]

[Comparative study on the effect of diet, exercise and iodine balneotherapy on blood rheologic parameters in diabetics within the scope of a 4 week health resort stay in Bad Hall].

作者信息

Moser M, Klieber M, Winkler R

出版信息

Wien Klin Wochenschr. 1985 Mar 29;97(7):327-31.

PMID:3993041
Abstract

A total of 123 spa patients with inadequately controlled diabetes mellitus was divided into the following 3 therapeutic groups: 1. therapeutic exercise alone, 2. iodine therapy with iodine brine (including drinking cure with "iodine-brine concentrate"), 3. remedial exercise plus iodine brine therapy. All patients received a rigidly controlled diabetic diet. The following parameters were determined at the beginning and at the end of the cure: whole blood and plasma viscosity, fibrinogen, blood glucose, total and HDL-cholesterol, triglycerides, HbA1c, alpha 2-macroglobulin, total protein, microhaematocrit. A significant improvement was found in the values of whole blood viscosity, cholesterol, triglycerides and blood glucose, indicative of a beneficial effect on metabolism, primarily due to the administered diet. The largest decreases were shown by blood viscosity, relative viscosity, triglycerides, cholesterol and HbA1c in group III, and by plasma viscosity in group II. alpha 2-Macroglobulins did not change. Fibrinogen was raised in groups I and III. The importance of the improved blood rheological properties is discussed, particularly with respect to reduced erythrocyte flexibility in diabetics.

摘要

总共123名糖尿病控制不佳的温泉疗养患者被分为以下3个治疗组:1. 单纯治疗性运动组;2. 碘盐水碘疗法组(包括饮用“碘盐水浓缩液”进行治疗);3. 治疗性运动加碘盐水疗法组。所有患者均接受严格控制的糖尿病饮食。在治疗开始时和结束时测定以下参数:全血和血浆粘度、纤维蛋白原、血糖、总胆固醇和高密度脂蛋白胆固醇、甘油三酯、糖化血红蛋白、α2-巨球蛋白、总蛋白、微量血细胞比容。发现全血粘度、胆固醇、甘油三酯和血糖值有显著改善,表明对代谢有有益影响,主要归因于所给予的饮食。第三组的全血粘度、相对粘度、甘油三酯、胆固醇和糖化血红蛋白下降幅度最大,第二组的血浆粘度下降幅度最大。α2-巨球蛋白没有变化。第一组和第三组的纤维蛋白原升高。讨论了血液流变学性质改善的重要性,特别是关于糖尿病患者红细胞柔韧性降低的问题。

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