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急性心肌梗死中的低钾血症、心律失常与早期预后

Hypokalemia, arrhythmias and early prognosis in acute myocardial infarction.

作者信息

Nordrehaug J E

出版信息

Acta Med Scand. 1985;217(3):299-306. doi: 10.1111/j.0954-6820.1985.tb02699.x.

Abstract

Serum potassium concentration was estimated on admission to hospital in 289 women and 785 men with acute myocardial infarction. The proportion of women in potassium subgroups was inversely related to serum potassium concentration, increasing from 8% at serum potassium greater than or equal to 5.2 mmol/l to 58% at less than or equal to 3 mmol/l. The frequency of diuretic therapy was also higher in women (35%) than in men (23%). The mortality rate was high at 3 months in patients with one or more arrhythmias (atrioventricular block grade 2, complete heart block, bundle branch block, atrial fibrillation, premature ventricular contractions, ventricular tachycardia) detected by conventional methods during the first 48 hours after admission. Hypokalemia (serum potassium less than or equal to 3.5 mmol/l) did not significantly predict increased occurrence of any of these arrhythmias. Small inhomogeneities of arrhythmias between the potassium groups may have been caused by digitalis therapy prior to admission. Hypokalemia on admission did not predict altered prognosis during the first 3 months.

摘要

对289名患有急性心肌梗死的女性和785名男性患者入院时的血清钾浓度进行了评估。钾亚组中的女性比例与血清钾浓度呈负相关,从血清钾大于或等于5.2 mmol/L时的8%增加到小于或等于3 mmol/L时的58%。女性使用利尿剂治疗的频率(35%)也高于男性(23%)。入院后最初48小时内通过传统方法检测出有一处或多处心律失常(二度房室传导阻滞、完全性心脏传导阻滞、束支传导阻滞、心房颤动、室性早搏、室性心动过速)的患者,3个月时死亡率很高。低钾血症(血清钾小于或等于3.5 mmol/L)并不能显著预测这些心律失常的发生率增加。钾组之间心律失常的微小不均一性可能是由入院前的洋地黄治疗引起的。入院时的低钾血症并不能预测最初3个月内预后的改变。

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