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髋关节骨折手术治疗后延迟下床活动会导致90天死亡率显著增加。

Delayed Postoperative Ambulation Results in a Significant Increase in 90-Day Mortality in Surgically Treated Hip Fractures.

作者信息

Wood Robert S, Vergun Maddie, Herrera Elizabeth, Krumrey Jacqueline

机构信息

Department of Orthopedic Surgery, Samaritan Health Services, Corvallis, OR, USA.

出版信息

Geriatr Orthop Surg Rehabil. 2025 Feb 9;16:21514593241308546. doi: 10.1177/21514593241308546. eCollection 2025.

Abstract

INTRODUCTION

Hip fractures in individuals aged 65 and older present a significant burden to patients, families, and health care systems. These fractures lead to increased morbidity, loss of autonomy in Activities of Daily Living (ADLs), prolonged hospitalization, and heightened mortality rates. Despite existing knowledge, there is a need for high-quality studies to understand mid- to long-term outcomes and the impact of postoperative variables on mortality.

METHODS

This retrospective matched case-control study analyzed patients who underwent operative management for hip fractures between August 1, 2021, and August 1, 2023, at a single Level II trauma center. Cases were defined as patients who expired between postoperative day 1 and ninety, while controls were patients alive at postoperative day 90. Cases and controls were matched by sex and age at the time of surgery. Patients over age 60, who underwent surgical treatment of a femoral neck or intertrochanteric fracture after receiving a preoperative block and were able to ambulate prior to their injury included. Cases and controls were matched based upon patient demographics including comorbidities. Major matched comorbidities were diabetes mellitus, hypertension, Chronic Obstructive Pulmonary Disease, and Coronary Artery Disease. A logistic regression was used to measure the association between in-hospital mobility and 90-day mortality.

RESULTS

The 90-day mortality rate was 9.5% (16/169). The mean age of participants was 85.7 years, with 62.5% female. No significant differences were found in hospital length of stay or operative time. However, 37.5% of cases were discharged on hospice compared to 3.1% of controls. Only 6.3% of cases ambulated in the hospital compared to 53.1% of controls (-value <.001). Logistic regression indicated that the odds of death were 17 times higher in patients who did not walk during their hospital stay (OR: 17.0, 95% CI: 2.91-326.0, -value: 0.01).

CONCLUSIONS

This study highlights the critical importance of early postoperative mobilization in reducing 90-day mortality in hip fracture patients. The findings reveal that patients who ambulated during hospital admission had significantly lower mortality rates. These results suggest that early mobilization could serve as a strong protective factor against early postoperative mortality.

摘要

引言

65岁及以上人群的髋部骨折给患者、家庭和医疗保健系统带来了沉重负担。这些骨折会导致发病率增加、日常生活活动(ADL)自主性丧失、住院时间延长以及死亡率上升。尽管已有相关知识,但仍需要高质量的研究来了解中长期结果以及术后变量对死亡率的影响。

方法

这项回顾性匹配病例对照研究分析了2021年8月1日至2023年8月1日期间在一家二级创伤中心接受髋部骨折手术治疗的患者。病例定义为术后第1天至第90天之间死亡的患者,而对照为术后第90天存活的患者。病例和对照在手术时按性别和年龄进行匹配。纳入年龄超过60岁、在接受术前阻滞治疗后接受股骨颈或转子间骨折手术治疗且受伤前能够行走的患者。病例和对照根据包括合并症在内的患者人口统计学特征进行匹配。主要的匹配合并症包括糖尿病、高血压、慢性阻塞性肺疾病和冠状动脉疾病。使用逻辑回归来衡量住院期间活动能力与90天死亡率之间的关联。

结果

90天死亡率为9.5%(16/169)。参与者的平均年龄为85.7岁,女性占62.5%。住院时间或手术时间未发现显著差异。然而,37.5%的病例在临终关怀下出院,而对照组为3.1%。住院期间能够行走的病例仅占6.3%,而对照组为53.1%(P值<.001)。逻辑回归表明,住院期间不能行走的患者死亡几率高出17倍(比值比:17.0,95%置信区间:2.91 - 326.0,P值:0.01)。

结论

本研究强调了术后早期活动对降低髋部骨折患者90天死亡率的至关重要性。研究结果显示,入院期间能够行走的患者死亡率显著较低。这些结果表明,早期活动可作为预防术后早期死亡的有力保护因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b16/11808765/74796498e713/10.1177_21514593241308546-fig1.jpg

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