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一例就诊于急诊科的皮肤利什曼病病例。

A Case of Cutaneous Leishmaniasis Presenting to the Emergency Department.

作者信息

Gordon Anne, Malik Adrienne N

机构信息

The University of Kansas School of Medicine, Kansas, Kansas, USA.

The University of Kansas Medical Center Emergency Department, Kansas, Kansas, USA.

出版信息

Open Access Emerg Med. 2025 Feb 7;17:85-89. doi: 10.2147/OAEM.S499748. eCollection 2025.

DOI:10.2147/OAEM.S499748
PMID:39936005
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11812455/
Abstract

In this case, we describe a case of cutaneous leishmaniasis, a protozoan disease not typically found in the United States, that presented to our emergency department (ED). The diagnosis was confirmed by the Center for Disease Control and Prevention (CDC) through a polymerase chain reaction (PCR) sample from the presenting skin lesion. The patient was a 43-year-old woman with history of a bite by an unknown organism while traveling by foot through Panama. She presented with a large, ulcerated lesion on her lower left shin. She was admitted on suspicion of leishmaniasis, and physicians of several specialties initiated a broad laboratory workup, collected wound cultures, prescribed antibiotics, and surgically repaired the lesion. The rapid recognition of leishmaniasis allowed for the patient to begin treatment before the definitive diagnosis returned, emphasizing the importance of knowledge of worldwide diseases and their presenting features for the ED physician.

摘要

在此病例中,我们描述了一例皮肤利什曼病,这是一种在美国不常见的原生动物疾病,该病例被送至我们的急诊科。疾病控制与预防中心(CDC)通过对患者皮肤病变部位进行聚合酶链反应(PCR)采样确诊了该病。患者为一名43岁女性,有在徒步穿越巴拿马期间被不明生物叮咬的病史。她左小腿下部出现一个巨大的溃疡病灶。她因疑似利什曼病入院,多个专科的医生开展了全面的实验室检查,采集伤口培养样本,开具抗生素,并对病灶进行了手术修复。对利什曼病的快速识别使患者在最终诊断结果出来之前就开始了治疗,这凸显了急诊科医生了解全球疾病及其临床表现特征的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b417/11812455/0ed0157bf837/OAEM-17-85-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b417/11812455/dad02bfaa4dd/OAEM-17-85-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b417/11812455/0ed0157bf837/OAEM-17-85-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b417/11812455/dad02bfaa4dd/OAEM-17-85-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b417/11812455/0ed0157bf837/OAEM-17-85-g0002.jpg

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本文引用的文献

1
Particulate and non-particle adjuvants in Leishmaniasis vaccine designs: A review.寄生虫和非寄生虫佐剂在利什曼病疫苗设计中的应用:综述。
J Vector Borne Dis. 2023 Apr-Jun;60(2):125-141. doi: 10.4103/0972-9062.361179.
2
Rapid Clinical Management of Leishmaniasis in Emergency Department: A Case Report with Clinical Review of Recent Literature.急诊科利什曼病的快速临床管理:一例病例报告及近期文献临床综述
Biology (Basel). 2020 Oct 23;9(11):351. doi: 10.3390/biology9110351.
3
Leishmaniasis.利什曼病。
J Infect. 2014 Nov;69 Suppl 1:S10-8. doi: 10.1016/j.jinf.2014.07.016. Epub 2014 Sep 17.
4
American Cutaneous Leishmaniasis in Panama: a historical review of entomological studies on anthropophilic Lutzomyia sand fly species.巴拿马的美洲皮肤利什曼病:关于嗜人卢氏白蛉物种的昆虫学研究历史回顾
Parasit Vectors. 2014 May 11;7:218. doi: 10.1186/1756-3305-7-218.
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Cutaneous leishmaniasis.皮肤利什曼病
Lancet Infect Dis. 2007 Sep;7(9):581-96. doi: 10.1016/S1473-3099(07)70209-8.