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接受根治性胃切除术的早期胃癌患者的预期寿命:与普通人群的比较。

Life expectancy of patients with early gastric cancer who underwent curative gastrectomy: comparison with the general population.

作者信息

Oh Seul Gi, Seong Ba Ool, Ko Chang Seok, Yook Jeong Hwan, Yoo Moon-Won, Kim Beom Su, Lee In-Seob, Gong Chung Sik, Min Sa Hong, Kim Seonok

机构信息

Division of Gastrointestinal Surgery, Department of Surgery, Asan Medical Center, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-Ro 43-Gil, Songpa-Gu, Seoul, 05505, Republic of Korea.

Department of Clinical Epidemiology and Biostatistics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

出版信息

Sci Rep. 2025 Feb 12;15(1):5229. doi: 10.1038/s41598-025-89158-y.

Abstract

Despite long-term survival reports in early gastric cancer, comparative life expectancy data with the general population is scarce. This study aimed to estimate patients' life expectancy and analyze disparities between early gastric cancer patients and the general population. Patients with stage 1 gastric cancer who underwent curative gastrectomy at Asan Medical Center were enrolled. Survival status was tracked via national health insurance records. Life expectancy was compared with general population data from the Korean Statistical Information Service database. The cohort comprised 8,637 patients (64.7% men, 17.3% aged 70+). Approximately 20% of patients underwent total gastrectomy. Life expectancy was favorable among women. Across all age groups, women's life expectancy generally exceeded 80 years. Male patients showed a reduced life expectancy, typically 4-10 years shorter than their female counterparts. The average life expectancy of male patients aged over 80 years who underwent total gastrectomy was about 5 years, whereas that of their female counterparts was approximately 7 years. Female patients undergoing distal gastrectomy did not demonstrate a statistically significant variance in life expectancy compared to the general population. This study provided comprehensive life expectancy data, organized by age, sex, and type of gastrectomy in a large stage 1 gastric cancer cohort. Our findings are expected to alleviate uncertainties and anxieties for individuals diagnosed with early gastric cancer.

摘要

尽管有早期胃癌长期生存的报告,但与普通人群相比的预期寿命数据却很匮乏。本研究旨在估计患者的预期寿命,并分析早期胃癌患者与普通人群之间的差异。纳入了在峨山医学中心接受根治性胃切除术的I期胃癌患者。通过国家健康保险记录追踪生存状况。将预期寿命与韩国统计信息服务数据库中的普通人群数据进行比较。该队列包括8637名患者(64.7%为男性,17.3%年龄在70岁及以上)。约20%的患者接受了全胃切除术。女性的预期寿命较好。在所有年龄组中,女性的预期寿命普遍超过80岁。男性患者的预期寿命缩短,通常比女性短4至10年。接受全胃切除术的80岁以上男性患者的平均预期寿命约为5年,而女性患者约为7年。接受远端胃切除术的女性患者与普通人群相比,预期寿命没有统计学上的显著差异。本研究提供了按年龄、性别和胃切除术类型整理的大型I期胃癌队列的综合预期寿命数据。我们的研究结果有望减轻早期胃癌患者的不确定性和焦虑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f29/11821818/2c9028c24262/41598_2025_89158_Fig1_HTML.jpg

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