Singh S B, Lang C M
Am J Vet Res. 1985 Feb;46(2):321-5.
Since Q fever is a potential risk to personnel working with small ruminants, the serologic status of sheep and goats received at a medical school animal facility for research was evaluated. A total of 104 sheep and 102 goats were subjected to blood sample-collection procedures on arrival, as well as after a 2-week quarantine period, and the sera were tested for Q fever specific antibodies by complement-fixation (CF) and microagglutination (MA) tests. The results from the 2 tests were compared and analyzed for seroconversion. On the basis of the CF test, 14 sheep and 3 goats were considered positive; these included 7 sheep and 2 goats that seroconverted during the quarantine period. In contrast, 1 sheep and 5 goats were found positive by the MA test, which also detected seroconversion of 1 sheep and 1 goat. The use of both tests for serologic surveillance of Q fever in sheep and goats increased the likelihood of detection. Management safety practices are also required to minimize the risk of disease transmission.
由于Q热对从事小反刍动物工作的人员构成潜在风险，因此对一所医学院动物设施接收用于研究的绵羊和山羊的血清学状况进行了评估。总共104只绵羊和102只山羊在抵达时以及经过2周隔离期后接受了血样采集程序，并通过补体结合（CF）和微量凝集（MA）试验检测血清中的Q热特异性抗体。对这两种试验的结果进行了比较和分析，以确定血清转化情况。根据CF试验，14只绵羊和3只山羊被视为阳性；其中包括7只在隔离期内发生血清转化的绵羊和2只山羊。相比之下，MA试验发现1只绵羊和5只山羊呈阳性，该试验还检测到1只绵羊和1只山羊发生血清转化。同时使用这两种试验对绵羊和山羊进行Q热血清学监测增加了检测的可能性。还需要采取管理安全措施，以尽量减少疾病传播风险。
