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口腔内良性病变的分布与患病率评估

An Assessment of the Distribution and Prevalence of Benign Intraoral Pathologies.

作者信息

Ertem Sinan Yasin, Uz Furkan

机构信息

School of Dentistry, Ankara Yildirim Beyazit University, Ankara 06010, Turkey.

出版信息

Diagnostics (Basel). 2025 Feb 3;15(3):350. doi: 10.3390/diagnostics15030350.

Abstract

The aim of this study is to evaluate the histopathological examinations of biopsy samples obtained from patients, and to determine the prevalence, age, and gender distribution of intraoral benign lesions. The study examines the distribution of all benign intraoral pathologies, including both soft tissue and hard tissue lesions, through which the goal is to contribute to clinical diagnostic processes. The histopathological evaluation results of 235 patients who underwent biopsy between 2021 and 2024 were retrospectively analyzed. Out of 235 patients, 123 (52.34%) were female and 112 (47.66%) were male. Lesions were categorized into two groups: soft tissue lesions and intraosseous lesions. The frequency, gender distribution, and age ranges of these lesions were assessed. Lesions exhibiting dysplasia or malignancy were excluded from the study. The most common benign intraoral lesion was identified as the radicular cyst, observed in 69 patients. The age range for radicular cysts varied from 8 to 80 years, with 30 cases in females and 39 in males. The most frequently encountered soft tissue lesion was traumatic fibroma, which constituted 25.33% (19 patients) of all soft tissue lesions. Traumatic fibromas were observed in patients aged between 12 and 62 years. In terms of overall prevalence among all benign intraoral pathological lesions, radicular cysts ranked first (29.36%), followed by periapical granulomas (15.31%), dentigerous cysts (11.06%), and traumatic fibromas (8.08%). The occurrence of soft tissue lesions was significantly higher in females (66.66%) compared to males (33.34%). There are no recent studies in the literature evaluating the prevalence and demographic distribution of intraoral benign lesions. The most common lesions diagnosed in the study are typically associated with inflammation and irritation. The most common hard tissue lesion was the radicular cyst, which was seen across a wide age range and in similar proportions in men and women. Among soft tissue lesions, traumatic fibroma was the most common, particularly in women, and was seen across a wide age range. In terms of gender distribution, soft tissue lesions were twice as common in women as in men.

摘要

本研究的目的是评估从患者获取的活检样本的组织病理学检查结果,并确定口腔内良性病变的患病率、年龄及性别分布。该研究考察了所有口腔内良性病变的分布情况,包括软组织和硬组织病变,以此为临床诊断过程提供帮助。对2021年至2024年间接受活检的235例患者的组织病理学评估结果进行了回顾性分析。在235例患者中,女性有123例(52.34%),男性有112例(47.66%)。病变分为两组:软组织病变和骨内病变。对这些病变的发生率、性别分布及年龄范围进行了评估。表现为发育异常或恶性的病变被排除在本研究之外。最常见的口腔内良性病变被确定为根尖囊肿,69例患者有此病变。根尖囊肿的年龄范围为8至80岁,女性30例,男性39例。最常遇到的软组织病变是创伤性纤维瘤,占所有软组织病变的25.33%(19例患者)。创伤性纤维瘤见于年龄在12至62岁的患者。在所有口腔内良性病理病变的总体患病率方面,根尖囊肿位居第一(29.36%),其次是根尖肉芽肿(15.31%)、含牙囊肿(11.06%)和创伤性纤维瘤(8.08%)。女性软组织病变的发生率(66.66%)显著高于男性(33.34%)。文献中近期没有评估口腔内良性病变患病率及人口统计学分布的研究。本研究中诊断出的最常见病变通常与炎症和刺激有关。最常见的硬组织病变是根尖囊肿,在广泛的年龄范围内均有发现,且男女比例相似。在软组织病变中,创伤性纤维瘤最为常见,尤其是在女性中,且在广泛的年龄范围内均有出现。在性别分布方面,软组织病变在女性中的发生率是男性的两倍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42f8/11816954/be44fac21f46/diagnostics-15-00350-g001.jpg

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