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头颈部血管异常:儿科概述。

Vascular Anomalies of the Head and Neck: A Pediatric Overview.

机构信息

Division of Pathology, Department of Paediatric Laboratory Medicine, Hospital for Sick Children, Toronto, ON, Canada.

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.

出版信息

Head Neck Pathol. 2021 Mar;15(1):59-70. doi: 10.1007/s12105-020-01236-x. Epub 2021 Mar 15.

DOI:10.1007/s12105-020-01236-x
PMID:33723757
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8010067/
Abstract

Vascular anomalies, further classified into vascular tumors and malformations, often involve the head and neck region of children. These entities may raise diagnostic dilemmas, as they often demonstrate heterogenous and overlapping histologic features. The aim of this paper is to provide an overview of the common vascular anomalies in the head and neck region of children. Specific entities discussed include infantile hemangioma, congenital hemangioma, tufted angioma, kaposiform hemangioendothelioma, and various vascular malformations. Clinicopathologic features and associated molecular associations are reviewed.

摘要

血管异常,进一步分为血管肿瘤和畸形,常涉及儿童的头颈部。这些实体可能会引起诊断上的困惑,因为它们通常表现出异质性和重叠的组织学特征。本文旨在概述儿童头颈部常见的血管异常。讨论的具体实体包括婴儿血管瘤、先天性血管瘤、丛状血管瘤、卡波西样血管内皮瘤和各种血管畸形。回顾了临床病理特征和相关的分子关联。

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本文引用的文献

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Vascular lesions of the head and neck: an update on classification and imaging review.头颈部血管病变:分类与影像学综述的最新进展
Insights Imaging. 2020 Feb 7;11(1):19. doi: 10.1186/s13244-019-0818-3.
2
Multifocal congenital hemangioma: Expanding the pathogenesis of "neonatal hemangiomatosis".多灶性先天性血管瘤:拓展“新生儿血管瘤病”的发病机制
Pediatr Dermatol. 2019 Sep;36(5):720-722. doi: 10.1111/pde.13814. Epub 2019 Jun 23.
3
The Pathogenesis of Port Wine Stain and Sturge Weber Syndrome: Complex Interactions between Genetic Alterations and Aberrant MAPK and PI3K Activation.葡萄酒色斑和脑面血管瘤病的发病机制:遗传改变与异常 MAPK 和 PI3K 激活之间的复杂相互作用。
Int J Mol Sci. 2019 May 7;20(9):2243. doi: 10.3390/ijms20092243.
4
Molecular changes associated with vascular malformations.与血管畸形相关的分子变化。
J Vasc Surg. 2019 Jul;70(1):314-326.e1. doi: 10.1016/j.jvs.2018.12.033. Epub 2019 Mar 25.
5
Vascular anomalies of the head and neck: current overview.头颈部血管异常:当前概述
Arch Craniofac Surg. 2018 Dec;19(4):243-247. doi: 10.7181/acfs.2018.02383. Epub 2018 Dec 27.
6
Clinical Practice Guideline for the Management of Infantile Hemangiomas.婴幼儿血管瘤管理临床实践指南。
Pediatrics. 2019 Jan;143(1). doi: 10.1542/peds.2018-3475.
7
Congenital tufted angioma: A multicenter retrospective study of 30 cases.先天性簇状血管瘤:30例多中心回顾性研究
Pediatr Dermatol. 2018 Nov;35(6):808-816. doi: 10.1111/pde.13683. Epub 2018 Oct 15.
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