Division of Pathology, Department of Paediatric Laboratory Medicine, Hospital for Sick Children, Toronto, ON, Canada.
Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
Head Neck Pathol. 2021 Mar;15(1):59-70. doi: 10.1007/s12105-020-01236-x. Epub 2021 Mar 15.
Vascular anomalies, further classified into vascular tumors and malformations, often involve the head and neck region of children. These entities may raise diagnostic dilemmas, as they often demonstrate heterogenous and overlapping histologic features. The aim of this paper is to provide an overview of the common vascular anomalies in the head and neck region of children. Specific entities discussed include infantile hemangioma, congenital hemangioma, tufted angioma, kaposiform hemangioendothelioma, and various vascular malformations. Clinicopathologic features and associated molecular associations are reviewed.
血管异常,进一步分为血管肿瘤和畸形,常涉及儿童的头颈部。这些实体可能会引起诊断上的困惑,因为它们通常表现出异质性和重叠的组织学特征。本文旨在概述儿童头颈部常见的血管异常。讨论的具体实体包括婴儿血管瘤、先天性血管瘤、丛状血管瘤、卡波西样血管内皮瘤和各种血管畸形。回顾了临床病理特征和相关的分子关联。