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[使用含白蛋白灌注液保存犬肾期间的活力测试]

[Viability testing during preservation of dog kidneys with an albumin-containing perfusion solution].

作者信息

Schröder K, Schuldt H H, Althaus P

出版信息

Z Urol Nephrol. 1979 Dec;72(12):885-91.

PMID:399419
Abstract

In models experiments on kidneys of dogs the prognostic significance of hydrodynamic, metabolic and enzymatic parameters in the machine preservation with an oxygenated-albumin-containing solution was tested. While the hydrodynamic and metabolic measuring values did not give a clear reference to different ischaemic restrictions of the functional capacity after autotransplantation, the activities of lactate dehydrogenase and N-acetyl-beta-D-glucosamidase in the perfusate proved to be suitable criteria of vitality. In this case the determination of lactate dehydrogenase is to be preferred on account of the smaller methodical expenditure.

摘要

在犬肾模型实验中,对含氧量白蛋白溶液机器保存中流体动力学、代谢和酶学参数的预后意义进行了测试。虽然流体动力学和代谢测量值并未明确反映自体移植后不同缺血对功能能力的限制,但灌注液中乳酸脱氢酶和N-乙酰-β-D-氨基葡萄糖苷酶的活性被证明是活力的合适标准。在这种情况下,考虑到方法上的花费较少,乳酸脱氢酶的测定更可取。

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