Fisher J C
Ann Plast Surg. 1985 Feb;14(2):158-61. doi: 10.1097/00000637-198502000-00012.
The oft-quoted 5-cm rule for melanoma excision is not valid. Substitute guidelines are offered and their scientific basis is discussed. A 1-2-3-cm rule is carefully outlined in terms of maximum rather than minimum margins, because little evidence exists to support the importance of wide excision limits in the treatment of melanoma.
经常被引用的黑色素瘤切除5厘米规则是无效的。本文提供了替代指南并讨论了其科学依据。根据最大切缘而非最小切缘详细阐述了1-2-3厘米规则，因为几乎没有证据支持广泛切除范围在黑色素瘤治疗中的重要性。
