Haschke F, Singer P, Baumgartner D, Steffan I, Schilling R, Lothaller H
Ann Nutr Metab. 1985;29(2):95-102. doi: 10.1159/000176966.
Zinc is an essential nutrient for growth and low intake can result in growth retardation. However, high zinc intake can affect copper metabolism. Therefore, data from a study of 10 male premature infants fed a cow's milk-based formula nonfortified with zinc (mean +/- SD = 1.4 +/- 0.1 mg X l-1) were compared with data of 10 similar infants fed the same formula fortified with zinc (4.1 +/- 0.3 mg X l-1). Growth, food intake, zinc and copper nutritional status were studied from 6 through 122 days of age. No differences in gain of weight, length and head circumference and in food intake were found. Serum zinc concentration was significantly (p less than 0.05) and hair zinc concentration was slightly higher in the infants fed the zinc-fortified formula at 122 days of age. Copper and ceruloplasmin concentrations in serum and hair copper concentration were similar in both groups at 122 days of age. The results suggest that feeding a formula nonfortified with zinc did not affect growth of male premature infants. Feeding a zinc-fortified formula on the other hand had no influence on copper nutritional status.
锌是生长所必需的营养素，摄入量低会导致生长发育迟缓。然而，锌摄入量过高会影响铜的代谢。因此，将10名喂食未强化锌的以牛奶为基础配方奶（平均±标准差=1.4±0.1毫克×升-1）的男性早产儿的研究数据，与10名喂食相同配方奶但强化了锌（4.1±0.3毫克×升-1）的类似婴儿的数据进行了比较。对6至122日龄的婴儿进行了生长、食物摄入量、锌和铜营养状况的研究。在体重、身长、头围增加和食物摄入量方面未发现差异。在122日龄时，喂食强化锌配方奶的婴儿血清锌浓度显著升高（p<0.05），头发锌浓度略高。两组在122日龄时血清铜和铜蓝蛋白浓度以及头发铜浓度相似。结果表明，喂食未强化锌的配方奶不会影响男性早产儿的生长。另一方面，喂食强化锌配方奶对铜营养状况没有影响。
